Prevention of COVID-19 Infection in the Medical Population: Possible Help from Anosmia?

Author(s): Giuseppe Chiarella*, Raffaella Pizzolato, Donatella Malanga, Davide Pisani, Ludovico Abenavoli, Pasquale Viola

Journal Name: Reviews on Recent Clinical Trials

Volume 15 , Issue 3 , 2020


Become EABM
Become Reviewer
Call for Editor

[1]
Wrapp D, Wang N, Corbett KS, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 367(6483): 1260-3.
[http://dx.doi.org/10.1126/science.abb2507] [PMID: 32075877]
[2]
Zhu N, Zhang D, Wang W, et al. China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020; 382(8): 727-33. [http://dx.doi.org/10.1056/NEJMoa2001017]. [PMID: 31978945].
[3]
2020.
[4]
Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol 2019; 17(3): 181-92. [http://dx.doi.org/10.1038/s41579-018-0118-9]. [PMID: 30531947].
[5]
Alexandra C. Walls Y-JP, M. Alexandra Tortorici, Abigail Wall, Andrew T. McGuire, David Veesler. Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein. bioRxiv 2020.
[6]
Wrapp D, Wang N, Corbett KS, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 367(6483): 1260-3.
[http://dx.doi.org/10.1126/science.abb2507 ]
[7]
Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol 2020; 5(4): 562-9. [http://dx.doi.org/10.1038/s41564-020-0688-y ]. [PMID: 32094589].
[9]
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395(10223): 497-506. [http://dx.doi.org/10.1016/S0140-6736(20)30183-5]. [PMID: 31986264].
[11]
Gentile I, Abenavoli L. COVID-19: Perspectives on the Potential Novel Global Threat. Rev Recent Clin Trials in press [http://dx.doi.org/10.2174/1574887115999200228100745 ]. [PMID: 32116200].
[12]
Bohmwald K, Gálvez NMS, Ríos M, Kalergis AM. Neurologic alterations due to respiratory virus infections. Front Cell Neurosci 2018; 12: 386. [http://dx.doi.org/10.3389/fncel.2018.00386]. [PMID: 30416428].
[13]
Swanson PA II, McGavern DB. Portals of viral entry into the central nervous systemThe Blood-Brain Barrier in Health and Disease. Boca Raton, FL: CRC Press 2015; pp. 23-47. [http://dx.doi.org/10.1201/b19299-3]
[14]
Baig AM, Khaleeq A, Ali U, Syeda H. Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms. ACS Chem Neurosci 2020; 11(7): 995-8. [http://dx.doi.org/10.1021/acschemneuro.0c00122]. [PMID: 32167747].
[15]
Durrant DM, Ghosh S, Klein RS. The Olfactory Bulb: An Immunosensory Effector Organ during Neurotropic Viral Infections. ACS Chem Neurosci 2016; 207(4): 464-9.
[16]
Ramadan N, Shaib H. Middle East respiratory syndrome coronavirus (MERS-CoV): A review. Germs. 2019 Mar 1;9(1):35-42.Bohmwald K, Gálvez NMS, Ríos M, Kalergis AM. Neurologic alterations due to respiratory virus infections. Front Cell Neurosci 2018; 12: 386.
[2]
Zhu N, Zhang D, Wang W, et al. China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020; 382(8): 727-33.
[http://dx.doi.org/10.1056/NEJMoa2001017] [PMID: 31978945]
[3]
2020.
[4]
Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol 2019; 17(3): 181-92.
[http://dx.doi.org/10.1038/s41579-018-0118-9] [PMID: 30531947]
[5]
Alexandra C. Walls Y-JP, M. Alexandra Tortorici, Abigail Wall, Andrew T. McGuire, David Veesler. Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein. bioRxiv 2020.
[6]
Wrapp D, Wang N, Corbett KS, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 367(6483): 1260-3.
[7]
Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol 2020; 5(4): 562-9.
[http://dx.doi.org/10.1038/s41564-020-0688-y ] [PMID: 32094589]
[9]
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395(10223): 497-506.
[http://dx.doi.org/10.1016/S0140-6736(20)30183-5] [PMID: 31986264]
[11]
Gentile I, Abenavoli L. COVID-19: Perspectives on the Potential Novel Global Threat. Rev Recent Clin Trials in press
[http://dx.doi.org/10.2174/1574887115999200228100745 ] [PMID: 32116200]
[12]
Bohmwald K, Gálvez NMS, Ríos M, Kalergis AM. Neurologic alterations due to respiratory virus infections. Front Cell Neurosci 2018; 12: 386.
[http://dx.doi.org/10.3389/fncel.2018.00386] [PMID: 30416428]
[13]
Swanson PA II, McGavern DB. Portals of viral entry into the central nervous systemThe Blood-Brain Barrier in Health and Disease. Boca Raton, FL: CRC Press 2015; pp. 23-47.
[http://dx.doi.org/10.1201/b19299-3]
[14]
Baig AM, Khaleeq A, Ali U, Syeda H. Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms. ACS Chem Neurosci 2020; 11(7): 995-8.
[http://dx.doi.org/10.1021/acschemneuro.0c00122] [PMID: 32167747]
[15]
Durrant DM, Ghosh S, Klein RS. The Olfactory Bulb: An Immunosensory Effector Organ during Neurotropic Viral Infections. ACS Chem Neurosci 2016; 207(4): 464-9.
[16]
Ramadan N, Shaib H. Middle East respiratory syndrome coronavirus (MERS-CoV): A review. Germs. 2019 Mar 1;9(1):35-42.Bohmwald K, Gálvez NMS, Ríos M, Kalergis AM. Neurologic alterations due to respiratory virus infections. Front Cell Neurosci 2018; 12: 386.


Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 15
ISSUE: 3
Year: 2020
Page: [244 - 245]
Pages: 2
DOI: 10.2174/1574887115666200603152637
Price: $65

Article Metrics

PDF: 26
HTML: 2