Polycystic ovary syndrome (PCOS) is a condition that affects about 15% of women of
reproductive age and is correlated with infertility, insulin resistance, and obesity. The etiology of
PCOS is multifactorial and genetic, endocrine, and metabolic causes are involved.
New evidence suggests a link between microorganisms residing in the digestive tracts of humans
and the development of PCOS. Moreover, an imbalance in the gut microbial community could be a
possible factor for the onset of insulin resistance and obesity. Hyperandrogenism, a key feature of
PCOS, could also play a critical role in shaping the microbiome community.
Probiotics could modify the gut microbiota and serve as a potential treatment for PCOS. Here we
disclose the association between PCOS and intestinal microbiota and the possible role of probiotics
as a new treatment approach.