Disseminated TB in an Immunocompetent Patient: A Case Report

Author(s): Malihe Hassan Nezhad, Alireza Ganadan, SeyedAhmad SeyedAlinaghi, Fatemeh Nili Ahmad Abadi, Seyed Ali Dehghan Manshadi, Mohammad Reza Salehi, Fereshte Ghiasvand, Seyedeh Rana Khatami*

Journal Name: Infectious Disorders - Drug Targets
Formerly Current Drug Targets - Infectious Disorders

Volume 21 , Issue 2 , 2021

Become EABM
Become Reviewer
Call for Editor

Graphical Abstract:


Background: Tuberculosis considered as a chronic infectious disease caused by Mycobacterium tuberculosis, may invade all organs but mainly affects the lungs. Overall, disseminated TB is rare in immunocompetent patients and its association with seborrheic keratosis has never been reported.

Case Presentation: We reported a 54-year-old man with a complaint prolonged fever, abdominal pain, weight loss and lymphadenopathy without any immunosuppression who was eventually treated based on the diagnosis of diffuse tuberculosis.

Keywords: Mycobacterium tuberculosis, disseminated tuberculosis, seborrheic keratosis, lymphadenopathy, diffuse tuberculosis, case report.

Ribeiro, S.; Trabulo, D. Cardoso, Oliveira.;Ana; Cremers,I. Disseminated tuberculosis in an immunocompetent patient: The answer is in the liver. GE Port. J. Gastroenterol., 2016, 208, 213.
Kaur, A.; Kucheria, M.; Gupta, R.; Thami, G.P.; Kundu, R. Extensive Multisystemic Disseminated Tuberculosis in an Immunocompetent Patient. J. Clin. Aesthet. Dermatol., 2018, 11(9), 42-46.
[PMID: 30319731]
Foroughi, M.; Mohaghegh Montazeri, S.; SeyedAlinaghi, S.; Moradmand Badie, B.; Heiydarpour, P.; Roosta, N.; Rasoolinejad, M.; Emadi Cochak, H. Incidence of isolation of Mycobacterium tuberculosis from blood samples in tuberculosis patients in Imam Khomeini Hospital, Tehran, Iran. Acta Med. Iran., 2011, 556, 559.
Jam, S.; Sabzvari, D.; SeyedAlinaghi, S.; Fattahi, F.; Jabbari, H. Frequency of Mycobacterium tuberculosis infection among Iranian patients with HIV/AIDS by PPD test. Acta Med. Iran., 2010, 67, 71.
Singh, J.; Dinkar, A. Positive outcome of pulmonary tuberculosis associated with extraordinary extensive extrapulmonary tuberculosis in an immunocompetent adult. Int. J. Mycobacteriol., 2018, 7(2), 183-185.
[http://dx.doi.org/10.4103/ijmy.ijmy_61_18] [PMID: 29900898]
Ma, G. Rui, Mao,R.; Miao, Q.; Zhou,B.T. A case of tuberculous endocarditis in an immunocompetent patient: difficulty with early diagnosis. Int. J. Cardiol., 2015, 497, 498.
Suárez, I.; Maria Fünger, S.; Jung, N.; Lehmann, C.; Reimer, R.P.; Mehrkens, D.; Bunte, A.; Plum, G.; Jaspers, N.; Schmidt, M.; Fätkenheuer, G.; Rybniker, J. Severe disseminated tuberculosis in HIV-negative refugees. Lancet Infect. Dis., 2019, 19(10), e352-e359.
[http://dx.doi.org/10.1016/S1473-3099(19)30162-8] [PMID: 31182290]
Saeed, M.; Khan, M.; Khan, A.; Margapuri, J.; Saliaj, M.; Ndebbio, I.; Ahmed, A.; Bachan, M.; Khan, Z.; Siegel, R. Lymphoma mimic: a case of disseminated tuberculous lymphadenitis in an immunocompetent patient. Crit. Care Med., 2019, 299.
Schlesinger, T.E.; Favre, C. Enhancing Outcomes in Seborrheic Keratosis: Using a Novel Treatment Solution. J. Drugs Dermatol., 2019, 18(7), s178-s182.
[PMID: 31336414]

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2021
Published on: 28 May, 2020
Page: [297 - 300]
Pages: 4
DOI: 10.2174/1871526520666200528152739
Price: $65

Article Metrics

PDF: 24