Diverse Routes for the Synthesis of Indole-Fused Complex Architecture from Simple Molecules

Author(s): Shivendra Singh, Suresh Singh Chauhan, Neeraj Kumar Sharma, Sunil Dutt, Keshav Lalit Ameta*

Journal Name: Mini-Reviews in Organic Chemistry

Volume 18 , Issue 2 , 2021

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Graphical Abstract:


Several easy, efficient and convenient procedures to access indoles fused heterocyclic systems are described in this review. These heterocyclic systems were synthesized from several cyclic or acyclic molecules via a variety of reactions such as Diels-Alder reaction, Michael addition, Morita- Baylis-Hillmann reaction and many other domino/Cascade approaches with high selectivity. Most of the given protocols in this review proceed through organocatalytic pathways; however, some underwent different catalytic and non-catalytic reactions.

Keywords: Analgesic, domino approach, indole heterocycles, multicomponent reactions, nootropic agents, organocatalysis, psychoanaleptic.

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Article Details

Year: 2021
Published on: 20 May, 2020
Page: [237 - 258]
Pages: 22
DOI: 10.2174/1570193X17999200521101255
Price: $65

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