Datura metel (Solanaceae) which is commonly known as thorn’s apple, Indian apple or devil’s trumpet
isan annual herb of temperate zones which is distributed all over the world. D. metel belongs to the family solanaceae.
From a longer period of time (37 A.D), species of this family had therapeutic uses. This article is based
on the review of different scientific backgrounds and studies regarding the traditional uses, phytochemistry, biochemical
constituents and pharmacological uses of D. metel. This review is based on the facts of the available
literature review. Different researchers conducted researches and studies on D. metel and confirmed the presence
of enormous chemical compounds like flavonoids, tropane alkaloids, tannins, saponins and withanolides. D. metel
has been found to be pharmacologically important species because of its different pharmacological and traditional
uses, such as hepatoprotective, antiviral effect, antibacterial effect, anti-asthmatic, analgesic, antipyretic and
nephroprotective effect, anticancer and antifungal effect. However, further in vivo and in vitro advanced studies
are required to carried out for the exact pharmacological mechanisms and for basis of clinical utility.