Aims: This study aims to elucidate the structural difference and biochemical properties
of bioactive compounds of microalgal biomasses.
Background: The structural difference and biochemical properties of bioactive compounds termed
as Water-Soluble Macromolecules (WSMs) are interested in evaluating their biological activities.
Methods: This study was performed to elucidate the structural difference and biochemical properties
of bioactive compounds termed as Water-Soluble Macromolecules (WSMs) isolated from defatted
microalgal biomasses of Botryococcus braunii and Dunaliella tertiolecta.
Results: The compositional analysis of both WSMs revealed that WSM-Bb is a hetero-macromolecule
consisting of various monosaccharides, whereas WSM-Dt was characterized as a homo--
macromolecule that mainly consists of glucose. Interestingly, WSM-Bb showed the significant tyrosinase
inhibitory activity with the increase of both the concentration and reaction time. Whereas
there was no significant inhibitory activity observed by WSM-Dt.
Conclusion: Inhibitory action of WSM-Bb toward both tyrosinase and tyrosine in either simultaneous
or separate reaction may be mainly due to the physical affinity of WSM-Bb. These results emphasize
the identification of the primary components of these WSMs and their relevance with the