Title:Expedition of Eudragit® Polymers in the Development of Novel Drug Delivery Systems
VOLUME: 17 ISSUE: 6
Author(s):Sunil Kumar Jain, Akhlesh K. Jain and Kuldeep Rajpoot*
Affiliation:Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (C.G.) 495 009, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (C.G.) 495 009, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (C.G.) 495 009
Keywords:Eudragit®, stomach-specific, colon-specific, ophthalmic, drug delivery, gene delivery.
Abstract:Eudragit® polymer has been widely used in film-coating for enhancing the quality of products
over other materials (e.g., shellac or sugar). Eudragit® polymers are obtained synthetically from the esters
of acrylic and methacrylic acid. For the last few years, they have shown immense potential in the
formulations of conventional, pH-triggered, and novel drug delivery systems for incorporating a vast
range of therapeutics including proteins, vitamins, hormones, vaccines, and genes. Different grades of
Eudragit® have been used for designing and delivery of therapeutics at a specific site via the oral route,
for instance, in stomach-specific delivery, intestinal delivery, colon-specific delivery, mucosal delivery.
Further, these polymers have also shown their great aptitude in topical and ophthalmic delivery. Moreover,
available literature evidences the promises of distinct Eudragit® polymers for efficient targeting of
incorporated drugs to the site of interest. This review summarizes some potential researches that are
being conducted by eminent scientists utilizing the distinct grades of Eudragit® polymers for efficient
delivery of therapeutics at various sites of interest.
