Title:Genomic and Molecular Perspectives of Host-pathogen Interaction and Resistance Strategies against White Rust in Oilseed Mustard
VOLUME: 21 ISSUE: 3
Author(s):Chatterjee Anupriya, Nirwan Shradha, Bandyopadhyay Prasun, Agnihotri Abha*, Sharma Pankaj, Malik Zainul Abdin and Shrivastava Neeraj*
Affiliation:Amity Institute of Microbial Technology, Amity University, Uttar Pradesh, Noida-201313, Amity Institute of Microbial Technology, Amity University, Uttar Pradesh, Noida-201313, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi-110067, Centre for Agricultural Biotechnology, Amity Institute of Microbial Technology, Amity University Uttar Pradesh, Noida-201313, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida-201313, Department of Biotechnology, Jamia Hamdard University, New Delhi-110062, Amity Institute of Microbial Technology, Amity University, Uttar Pradesh, Noida-201313
Keywords:Albugo candida, brassica, effector molecules, resistance (R) genes, nucleotide-binding leucine-rich repeats (NLRs),
white rust resistance.
Abstract:
Oilseed brassicas stand as the second most valuable source of vegetable oil and the third
most traded one across the globe. However, the yield can be severely affected by infections caused by
phytopathogens. White rust is a major oomycete disease of oilseed brassicas resulting in up to 60%
yield loss globally. So far, success in the development of oomycete resistant Brassicas through conventional
breeding has been limited. Hence, there is an imperative need to blend conventional and
frontier biotechnological means to breed for improved crop protection and yield.
This review provides a deep insight into the white rust disease and explains the oomycete-plant molecular
events with special reference to Albugo candida describing the role of effector molecules, A.
candida secretome, and disease response mechanism along with nucleotide-binding leucine-rich repeat
receptor (NLR) signaling. Based on these facts, we further discussed the recent progress and future
scopes of genomic approaches to transfer white rust resistance in the susceptible varieties of
oilseed brassicas, while elucidating the role of resistance and susceptibility genes. Novel genomic
technologies have been widely used in crop sustainability by deploying resistance in the host. Enrichment
of NLR repertoire, over-expression of R genes, silencing of avirulent and disease susceptibility
genes through RNA interference and CRSPR-Cas are technologies which have been successfully applied
against pathogen-resistance mechanism. The article provides new insight into Albugo and Brassica
genomics which could be useful for producing high yielding and WR resistant oilseed cultivars
across the globe.