Background/Aim: Use of nanomaterials in healthcare applications increases in parallel to
technological developments. It is frequently utilized in diagnostic procedures, medications and therapeutic
implementations. Nanomaterials take place among key components of medical implants,
which might be responsible for certain toxic effects on human health at nano-level. In this review,
nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their
effects on human health are discussed.
Materials and Methods: A detailed review of related literature was performed and evaluated as per
nanomaterials and medical implants.
Results: The nanotoxic effects of the materials applied to human body and the determination of its
toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial
assessment considering the properties of these materials.
Conclusion: There are limited studies in the literature regarding the toxic effects of nanomaterials
used in medical implants. Although these implants are potentially biocompatible and biodegradable,
it is highly important to discuss nanotoxicological characteristics of medical implants.