Novel Technologies and Nanotoxicology of Medical Implants

Author(s): Ramazan Akçan*, Halit C. Aydogan, Mahmut Ş. Yıldırım, Burak Taştekin, Necdet Sağlam

Journal Name: Current Analytical Chemistry

Volume 17 , Issue 8 , 2021

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Graphical Abstract:


Background/Aim: Use of nanomaterials in healthcare applications increases in parallel to technological developments. It is frequently utilized in diagnostic procedures, medications and therapeutic implementations. Nanomaterials take place among key components of medical implants, which might be responsible for certain toxic effects on human health at nano-level. In this review, nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their effects on human health are discussed.

Materials and Methods: A detailed review of related literature was performed and evaluated as per nanomaterials and medical implants.

Results: The nanotoxic effects of the materials applied to human body and the determination of its toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial assessment considering the properties of these materials.

Conclusion: There are limited studies in the literature regarding the toxic effects of nanomaterials used in medical implants. Although these implants are potentially biocompatible and biodegradable, it is highly important to discuss nanotoxicological characteristics of medical implants.

Keywords: Biomaterials, medical implants, nanomaterials, nanotechnology, nanotoxicology, therapeutic implementations.

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Article Details

Year: 2021
Published on: 06 May, 2020
Page: [1133 - 1140]
Pages: 8
DOI: 10.2174/1573411016999200507104128
Price: $65

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PDF: 165