Nanoparticles (Np) are the 21st century material in supreme formulations due to their unique properties and
design. In review, systematic discussion of the synthesis, characterization, bio-applications and risks of AgNps (Silver
Nanoparticles) specially highlighting anticancer activity envisaging mechanisms as well as therapeutic approaches for
cancer. Ag-Nps mainly possess toxicological concern.
Benefits and Risk: AgNps have beneficial approaches for cancer treatment and angiogenesis-related diseases like
rheumatoid arthritis, atherosclerosis, diabetic psoriasis, retinopathy, endometriosis and adiposity.
Ag-Nps induced cytotoxicity through oxidative stress by the ROS (Reactive Oxygen Species) generation could be
measured as dependent on different properties such as nanoparticle shape, size, agglomeration, concentration and
Result: The advancing nanotechnology-based therapy need to be devised better, and it should offload the hitches of
prevailing treatment approaches. Essential studies are required to explain the synergistic effect of two different cytotoxic