Nanoparticles (Np) are the 21st century material in supreme formulations due to their
unique properties and design. In review, systematic discussion of the synthesis, characterization,
bio-applications, and risks of AgNps (Silver Nanoparticles) especially highlighting anticancer activity
envisaging mechanisms as well as therapeutic approaches for cancer. Ag-Nps mainly possess
Benefits and Risk: AgNps have beneficial approaches for cancer treatment and angiogenesisrelated
diseases like rheumatoid arthritis, atherosclerosis, diabetic psoriasis, retinopathy, endometriosis,
Ag-Nps induced cytotoxicity through oxidative stress by the ROS (Reactive Oxygen Species) generation
could be measured as dependent on different properties, such as nanoparticle shape, size,
agglomeration, concentration, and aggregation.
Results: The advancing nanotechnology-based therapy needs to be devised better, and it should
offload the hitches of prevailing treatment approaches. Essential studies are required to explain the
synergistic effect of two different cytotoxic agents.