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Current Vascular Pharmacology

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ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

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Review Article

Cardiovascular Benefits of Extended-Time Nocturnal Hemodialysis

Author(s): Athanasios Roumeliotis, Stefanos Roumeliotis, Christopher Chan and Andreas Pierratos*

Volume 19, Issue 1, 2021

Published on: 01 April, 2020

Page: [21 - 33] Pages: 13

DOI: 10.2174/1570161118666200401112106

Price: $65

Abstract

Hemodialysis (HD) remains the most utilized treatment for End-Stage Kidney Disease (ESKD) globally, mainly as conventional HD administered in 4 h sessions thrice weekly. Despite advances in HD delivery, patients with ESKD carry a heavy cardiovascular morbidity and mortality burden. This is associated with cardiac remodeling, left ventricular hypertrophy (LVH), myocardial stunning, hypertension, decreased heart rate variability, sleep apnea, coronary calcification and endothelial dysfunction. Therefore, intensive HD regimens closer to renal physiology were developed. They include longer, more frequent dialysis or both. Among them, Nocturnal Hemodialysis (NHD), carried out at night while asleep, provides efficient dialysis without excessive interference with daily activities. This regimen is closer to the physiology of the native kidneys. By providing increased clearance of small and middle molecular weight molecules, NHD can ameliorate uremic symptoms, control hyperphosphatemia and improve quality of life by allowing a liberal diet and free time during the day. Lastly, it improves reproductive biology leading to successful pregnancies. Conversion from conventional to NHD is followed by improved blood pressure control with fewer medications, regression of LVH, improved LV function, improved sleep apnea, and stabilization of coronary calcifications. These beneficial effects have been associated, among others, with better extracellular fluid volume control, improved endothelial- dependent vasodilation, decreased total peripheral resistance, decreased plasma norepinephrine levels and restoration of heart rate variability. Some of these effects represent improvements in outcomes used as surrogates of hard outcomes related to cardiovascular morbidity and mortality. In this review, we consider the cardiovascular effects of NHD.

Keywords: Cardiovascular disease, cardiac morphology, carbamylated albumin, home hemodialysis, intensive hemodialysis, myocardial stunning, nocturnal hemodialysis, vascular calcification.

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[1]
Unruh ML, Larive B, Chertow GM, et al. Effects of 6-times-weekly versus 3-times-weekly hemodialysis on depressive symptoms and self-reported mental health: Frequent Hemodialysis Network (FHN) Trials. Am J Kidney Dis 2013; 61(5): 748-58.
[http://dx.doi.org/10.1053/j.ajkd.2012.11.047] [PMID: 23332990]
[2]
Karur GR, Wald R, Goldstein MB, et al. Association between conversion to in-center nocturnal hemodialysis and right ventricular remodeling. Nephrol Dial Transplant 2018; 33(6): 1010-6.
[http://dx.doi.org/10.1093/ndt/gfx232] [PMID: 28992094]
[3]
Collins AJ, Foley RN, Chavers B, et al. United States renal data system 2011 annual data report: atlas of chronic kidney disease & end-stage renal disease in the United States Am J Kidney Dis 2012; 59(1 Suppl 1): A7,e1-420.
[http://dx.doi.org/10.1053/j.ajkd.2011.11.015] [PMID: 22177944]
[4]
McCullough PA, Chan CT, Weinhandl ED, et al. Intensive hemodialysis, left ventricular hypertrophy, and cardiovascular diseaseAm J Kidney Dis 2016; 68(5S1): S5-S14.
[http://dx.doi.org/10.1053/j.ajkd.2016.05.025] [PMID: 27772643]
[5]
Susantitaphong P, Koulouridis I, Balk EM, Madias NE, Jaber BL. Effect of frequent or extended hemodialysis on cardiovascular pa-rameters: a meta-analysis. Am J Kidney Dis 2012; 59(5): 689-99.
[http://dx.doi.org/10.1053/j.ajkd.2011.12.020] [PMID: 22370022]
[6]
Collins AJ, Foley RN, Herzog C, et al. Excerpts from the US renal data system 2009 annual data report. Am J Kidney Dis 2010; 55(1)(Suppl. 1): S1-A7.
[http://dx.doi.org/10.1053/j.ajkd.2009.10.009]] [PMID: 20082919]
[7]
Wald R, Yan AT, Perl J, et al. Regression of left ventricular mass following conversion from conventional hemodialysis to thrice weekly in-centre nocturnal hemodialysis. BMC Nephrol 2012; 13: 3.
[http://dx.doi.org/10.1186/1471-2369-13-3] [PMID: 22260388]
[8]
Longenecker JC, Coresh J, Powe NR, et al. Traditional cardiovascular disease risk factors in dialysis patients compared with the general population: the choice Study. J Am Soc Nephrol 2002; 13(7): 1918-27.
[http://dx.doi.org/10.1097/01.ASN.0000019641.41496.1E] [PMID: 12089389]
[9]
Culleton BF, Walsh M, Klarenbach SW, et al. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial. JAMA 2007; 298(11): 1291-9.
[http://dx.doi.org/10.1001/jama.298.11.1291] [PMID: 17878421]
[10]
Pierratos A, McFarlane P, Chan CT. Quotidian dialysis--update 2005. Curr Opin Nephrol Hypertens 2005; 14(2): 119-24.
[http://dx.doi.org/10.1097/00041552-200503000-00006] [PMID: 15687837]
[11]
Bleyer AJ, Russell GB, Satko SG. Sudden and cardiac death rates in hemodialysis patients. Kidney Int 1999; 55(4): 1553-9.
[http://dx.doi.org/10.1046/j.1523-1755.1999.00391.x] [PMID: 10201022]
[12]
Foley RN, Gilbertson DT, Murray T, Collins AJ. Long interdialytic interval and mortality among patients receiving hemodialysis. N Engl J Med 2011; 365(12): 1099-107.
[http://dx.doi.org/10.1056/NEJMoa1103313] [PMID: 21992122]
[13]
DePalma JR, Pecker EA, Gordon A, Maxwell MH. A new compact automatic home hemodialysis system. Trans Am Soc Artif Intern Organs 1968; 14: 152-9.
[PMID: 5701525]
[14]
Louis B, Patel TG, Pinedo A, Snyder D, Gorfein P. Clinical experience with long-term 5 days-a-week hemodialysis. Proc Clin Dial Transplant Forum 1975; 5: 58-60.
[PMID: 785464]
[15]
Snyder D, Louis BM, Gorfien P, Mordujovich J. Clinical experience with long-term brief, ‘daily’ haemodialysis. Proc Eur Dial Transplant Assoc 1975; 11: 128-35.
[PMID: 1197245]
[16]
Buoncristiani U, Quintaliani G, Cozzari M, Giombini L, Ragaiolo M. Daily dialysis: long-term clinical metabolic results. Kidney Int Suppl 1988; 24: S137-40.
[PMID: 3163035]
[17]
Barber S, Appleton DR, Kerr DN. Adequate dialysis. Nephron 1975; 14(2): 209-27.
[http://dx.doi.org/10.1159/000180449] [PMID: 1128745]
[18]
Lowrie EG, Laird NM, Parker TF, Sargent JA. Effect of the hemodialysis prescription of patient morbidity: report from the National Cooperative Dialysis Study. N Engl J Med 1981; 305(20): 1176-81.
[http://dx.doi.org/10.1056/NEJM198111123052003] [PMID: 7027040]
[19]
Eknoyan G, Beck GJ, Cheung AK, et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 2002; 347(25): 2010-9.
[http://dx.doi.org/10.1056/NEJMoa021583] [PMID: 12490682]
[20]
Briggs JP. Evidence-based medicine in the dialysis unit: a few lessons from the USRDS and the NCDS and HEMO trials. Semin Dial 2004; 17(2): 136-41.
[http://dx.doi.org/10.1111/j.0894-0959.2004.17211.x] [PMID: 15043616]
[21]
Sargent JA, Lowrie EG. Which mathematical model to study uremic toxicity? National cooperative dialysis study. Clin Nephrol 1982; 17(6): 303-14.
[PMID: 7049475]
[22]
Gotch FA, Sargent JA. A mechanistic analysis of the National Cooperative Dialysis Study (NCDS). Kidney Int 1985; 28(3): 526-34.
[http://dx.doi.org/10.1038/ki.1985.160] [PMID: 3934452]
[23]
Pierratos A. Daily hemodialysis: why the renewed interest? Am J Kidney Dis 1998; 32(6)(Suppl. 4): S76-82.
[http://dx.doi.org/10.1016/S0272-6386(98)70166-0] [PMID: 9892370]
[24]
Jaber BL, Finkelstein FO, Glickman JD, et al. Scope and design of the following rehabilitation, economics and everyday-dialysis outcome measurements (FREEDOM) study. Am J Kidney Dis 2009; 53(2): 310-20.
[http://dx.doi.org/10.1053/j.ajkd.2008.07.013] [PMID: 18823688]
[25]
Pierratos A, Ouwendyk M, Francoeur R, et al. Nocturnal hemodialysis: three-year experience. J Am Soc Nephrol 1998; 9(5): 859-68.
[PMID: 9596084]
[26]
Pierratos A. Nocturnal home haemodialysis: an update on a 5-year experience. Nephrol Dial Transplant 1999; 14(12): 2835-40.
[http://dx.doi.org/10.1093/ndt/14.12.2835] [PMID: 10570083]
[27]
Agar JW. Nocturnal haemodialysis in Australia and New Zealand. Nephrology (Carlton) 2005; 10(3): 222-30.
[http://dx.doi.org/10.1111/j.1440-1797.2005.00409.x] [PMID: 15958033]
[28]
Lockridge RS, Albert J, Anderson H, et al. Nightly home hemodialysis: fifteen months of experience in Lynchburg, Virginia. Home Hemodial Int 1999; 3(1): 23-8.
[http://dx.doi.org/10.1111/hdi.1999.3.1.23] [PMID: 28455856]
[29]
Charra B, Calemard E, Ruffet M, et al. Survival as an index of adequacy of dialysis. Kidney Int 1992; 41(5): 1286-91.
[http://dx.doi.org/10.1038/ki.1992.191] [PMID: 1614043]
[30]
Lacson E Jr, Xu J, Suri RS, et al. Survival with three-times weekly in-center nocturnal versus conventional hemodialysis. J Am Soc Nephrol 2012; 23(4): 687-95.
[http://dx.doi.org/10.1681/ASN.2011070674] [PMID: 22362905]
[31]
Rocco MV, Lockridge RS Jr, Beck GJ, et al. The effects of frequent nocturnal home hemodialysis: the frequent hemodialysis network nocturnal trial. Kidney Int 2011; 80(10): 1080-91.
[http://dx.doi.org/10.1038/ki.2011.213] [PMID: 21775973]
[32]
Diaz-Buxo JA, White SA, Himmele R. Frequent hemodialysis: a critical review. Semin Dial 2013; 26(5): 578-89.
[http://dx.doi.org/10.1111/sdi.12110] [PMID: 23834104]
[33]
House AA, Wanner C, Sarnak MJ, et al. Heart failure in chronic kidney disease: conclusions from a kidney disease: improving global outcomes (KDIGO) controversies conference. Kidney Int 2019; 95(6): 1304-17.
[http://dx.doi.org/10.1016/j.kint.2019.02.022] [PMID: 31053387]
[34]
de Simone G, de Divitiis O. Extracellular matrix and left ventricular mechanics in overload hypertrophy. Adv Clin Path 2002; 6(1): 3-10.
[PMID: 17582942]
[35]
Chan CT, Li GH, Valaperti A, Liu P. Intensive Hemodialysis Preserved Cardiac injury. ASAIO J 2015; 61(5): 613-9.
[http://dx.doi.org/10.1097/MAT.0000000000000255] [PMID: 26164598]
[36]
London GM. Cardiovascular disease in chronic renal failure: pathophysiologic aspects. Semin Dial 2003; 16(2): 85-94.
[http://dx.doi.org/10.1046/j.1525-139X.2003.16023.x] [PMID: 12641870]
[37]
Inrig JK, Patel UD, Gillespie BS, Hasselblad V, Himmelfarb J, Reddan D, et al. Relationship between interdialytic weight gain and blood pressure among prevalent hemodialysis patients. Am J Kidney Dis 2007; 50(1): 108-18.
[http://dx.doi.org/10.1053/j.ajkd.2007.04.020]
[38]
Merchant A, Wald R, Goldstein MB, et al. Relationship between different blood pressure measurements and left ventricular mass by cardiac magnetic resonance imaging in end-stage renal disease. J Am Soc Hypertens 2015; 9(4): 275-84.
[http://dx.doi.org/10.1016/j.jash.2015.01.011] [PMID: 25753299]
[39]
Sesti G, Sciacqua A, Scozzafava A, et al. Effects of growth hormone and insulin-like growth factor-1 on cardiac hypertrophy of hypertensive patients. J Hypertens 2007; 25(2): 471-7.
[http://dx.doi.org/10.1097/HJH.0b013e3280112b63] [PMID: 17211256]
[40]
Glassock RJ, Pecoits-Filho R, Barberato SH. Left ventricular mass in chronic kidney disease and ESRD. Clin J Am Soc Nephrol 2009; 4(Suppl. 1): S79-91.
[http://dx.doi.org/10.2215/CJN.04860709] [PMID: 19996010]
[41]
Vanholder R, De Smet R, Glorieux G, et al. Review on uremic toxins: classification, concentration, and interindividual variability. Kidney Int 2003; 63(5): 1934-43.
[http://dx.doi.org/10.1046/j.1523-1755.2003.00924.x] [PMID: 12675874]
[42]
Marchais SJ, Metivier F, Guerin AP, London GM. Association of hyperphosphataemia with haemodynamic disturbances in end-stage renal disease. Nephrol Dial Transplant 1999; 14(9): 2178-83.
[http://dx.doi.org/10.1093/ndt/14.9.2178] [PMID: 10489228]
[43]
Gross ML, Ritz E. Hypertrophy and fibrosis in the cardiomyopathy of uremia--beyond coronary heart disease. Semin Dial 2008; 21(4): 308-18.
[http://dx.doi.org/10.1111/j.1525-139X.2008.00454.x] [PMID: 18627569]
[44]
Piovesan A, Molineri N, Casasso F, et al. Left ventricular hypertrophy in primary hyperparathyroidism. Effects of successful parathy-roidectomy. Clin Endocrinol (Oxf) 1999; 50(3): 321-8.
[http://dx.doi.org/10.1046/j.1365-2265.1999.00651.x] [PMID: 10435057]
[45]
Hu MC, Kuro-o M, Moe OW. The emerging role of Klotho in clinical nephrology. Nephrol Dial Transplant 2012; 27(7): 2650-7.
[http://dx.doi.org/10.1093/ndt/gfs160] [PMID: 22802580]
[46]
Kuro-o M, Matsumura Y, Aizawa H, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997; 390(6655): 45-51.
[http://dx.doi.org/10.1038/36285] [PMID: 9363890]
[47]
Yang K, Wang C, Nie L, et al. Klotho protects against indoxyl sulphate-induced myocardial hypertrophy. J Am Soc Nephrol 2015; 26(10): 2434-46.
[http://dx.doi.org/10.1681/ASN.2014060543] [PMID: 25804281]
[48]
Silberberg JS, Barre PE, Prichard SS, Sniderman AD. Impact of left ventricular hypertrophy on survival in end-stage renal disease. Kidney Int 1989; 36(2): 286-90.
[http://dx.doi.org/10.1038/ki.1989.192] [PMID: 2528654]
[49]
Zoccali C, Benedetto FA, Mallamaci F, et al. Left ventricular mass monitoring in the follow-up of dialysis patients: prognostic value of left ventricular hypertrophy progression. Kidney Int 2004; 65(4): 1492-8.
[http://dx.doi.org/10.1111/j.1523-1755.2004.00530.x] [PMID: 15086493]
[50]
London GM, Pannier B, Guerin AP, et al. Alterations of left ventricular hypertrophy in and survival of patients receiving hemodialysis: follow-up of an interventional study. J Am Soc Nephrol 2001; 12(12): 2759-67.
[PMID: 11729246]
[51]
Wald R, Goldstein MB, Wald RM, et al. Correlates of left ventricular mass in chronic hemodialysis recipients. Int J Cardiovasc Imaging 2014; 30(2): 349-56.
[http://dx.doi.org/10.1007/s10554-013-0337-0] [PMID: 24293047]
[52]
Chan CT, Floras JS, Miller JA, Richardson RM, Pierratos A. Regression of left ventricular hypertrophy after conversion to nocturnal hemodialysis. Kidney Int 2002; 61(6): 2235-9.
[http://dx.doi.org/10.1046/j.1523-1755.2002.00362.x] [PMID: 12028465]
[53]
Chan C, Floras JS, Miller JA, Pierratos A. Improvement in ejection fraction by nocturnal haemodialysis in end-stage renal failure patients with coexisting heart failure. Nephrol Dial Transplant 2002; 17(8): 1518-21.
[http://dx.doi.org/10.1093/ndt/17.8.1518] [PMID: 12147805]
[54]
Chertow GM, Levin NW, Beck GJ, et al. In-center hemodialysis six times per week versus three times per week. N Engl J Med 2010; 363(24): 2287-300.
[http://dx.doi.org/10.1056/NEJMoa1001593] [PMID: 21091062]
[55]
Chan CT, Greene T, Chertow GM, et al. Determinants of left ventricular mass in patients on hemodialysis: Frequent Hemodialysis Network (FHN) Trials. Circ Cardiovasc Imaging 2012; 5(2): 251-61.
[http://dx.doi.org/10.1161/CIRCIMAGING.111.969923] [PMID: 22360996]
[56]
Liu F, Sun Y, Xu T, et al. Effect of nocturnal hemodialysis versus conventional hemodialysis on end-stage renal disease: a meta-analysis and systematic review. PLoS One 2017; 12(1)e0169203
[http://dx.doi.org/10.1371/journal.pone.0169203] [PMID: 28107451]
[57]
Ong JP, Wald R, Goldstein MB, et al. Left ventricular strain analysis using cardiac magnetic resonance imaging in patients undergoing in-centre nocturnal haemodialysis. Nephrology (Carlton) 2019; 24(5): 557-63.
[http://dx.doi.org/10.1111/nep.13404] [PMID: 29785733]
[58]
Trinh E, Chan CT. Intensive home hemodialysis results in regression of left ventricular hypertrophy and better clinical outcomes. Am J Nephrol 2016; 44(4): 300-7.
[http://dx.doi.org/10.1159/000449452] [PMID: 27640181]
[59]
Dell’Italia LJ. The right ventricle: anatomy, physiology, and clinical importance. Curr Probl Cardiol 1991; 16(10): 653-720.
[http://dx.doi.org/10.1016/0146-2806(91)90009-Y] [PMID: 1748012]
[60]
Wald R, Goldstein MB, Perl J, et al. The Association between conversion to in-centre nocturnal hemodialysis and left ventricular mass regression in patients with end-stage renal disease. Can J Cardiol 2016; 32(3): 369-77.
[http://dx.doi.org/10.1016/j.cjca.2015.07.004] [PMID: 26386732]
[61]
Chan CT, Kaysen GA, Beck GJ, et al. Changes in biomarker profile and left ventricular hypertrophy regression: results from the frequent hemodialysis network trials. Am J Nephrol 2018; 47(3): 208-17.
[http://dx.doi.org/10.1159/000488003] [PMID: 29621747]
[62]
Chan CT, Arab S, Carasso S, et al. Impact of frequent nocturnal hemodialysis on myocardial mechanics and cardiomyocyte gene expression. Circ Cardiovasc Imaging 2012; 5(4): 474-80.
[http://dx.doi.org/10.1161/CIRCIMAGING.111.971606] [PMID: 22647434]
[63]
Haddad F, Doyle R, Murphy DJ, Hunt SA. Right ventricular function in cardiovascular disease, part II: pathophysiology, clinical im-portance, and management of right ventricular failure. Circulation 2008; 117(13): 1717-31.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.107.653584] [PMID: 18378625]
[64]
Girsberger M, Thenganatt J, Chan CT. Correction of pulmonary hypertension with intensive hemodialysis: A case report. Hemodial Int 2019; 23(2): E49-52.
[http://dx.doi.org/10.1111/hdi.12691] [PMID: 30786137]
[65]
Friesen T, Jassal DS, Zhu M, et al. Cardiovascular remodeling during long-term nocturnal home hemodialysis. Clin Exp Nephrol 2015; 19(3): 514-20.
[http://dx.doi.org/10.1007/s10157-014-0992-z] [PMID: 24894700]
[66]
Tripepi G, Benedetto FA, Mallamaci F, Tripepi R, Malatino L, Zoccali C. Left atrial volume monitoring and cardiovascular risk in patients with end-stage renal disease: a prospective cohort study. J Am Soc Nephrol 2007; 18(4): 1316-22.
[http://dx.doi.org/10.1681/ASN.2006080881] [PMID: 17360950]
[67]
Atar I, Konaş D, Açikel S, et al. Frequency of atrial fibrillation and factors related to its development in dialysis patients. Int J Cardiol 2006; 106(1): 47-51.
[http://dx.doi.org/10.1016/j.ijcard.2004.12.048] [PMID: 16321665]
[68]
Jefferies HJ, Virk B, Schiller B, Moran J, McIntyre CW. Frequent hemodialysis schedules are associated with reduced levels of dialysis-induced cardiac injury (myocardial stunning). Clin J Am Soc Nephrol 2011; 6(6): 1326-32.
[http://dx.doi.org/10.2215/CJN.05200610] [PMID: 21597028]
[69]
Selby NM, Lambie SH, Camici PG, Baker CS, McIntyre CW. Occurrence of regional left ventricular dysfunction in patients undergoing standard and biofeedback dialysis. Am J Kidney Dis 2006; 47(5): 830-41.
[http://dx.doi.org/10.1053/j.ajkd.2006.01.012] [PMID: 16632022]
[70]
Flythe JE, Kimmel SE, Brunelli SM. Rapid fluid removal during dialysis is associated with cardiovascular morbidity and mortality. Kidney Int 2011; 79(2): 250-7.
[http://dx.doi.org/10.1038/ki.2010.383] [PMID: 20927040]
[71]
Johansen KL, Zhang R, Huang Y, et al. Survival and hospitalization among patients using nocturnal and short daily compared to conventional hemodialysis: a USRDS study. Kidney Int 2009; 76(9): 984-90.
[http://dx.doi.org/10.1038/ki.2009.291] [PMID: 19692997]
[72]
Cheigh JS, Milite C, Sullivan JF, Rubin AL, Stenzel KH. Hypertension is not adequately controlled in hemodialysis patients. Am J Kidney Dis 1992; 19(5): 453-9.
[http://dx.doi.org/10.1016/S0272-6386(12)80954-1] [PMID: 1585934]
[73]
Kundhal K, Pierratos A, Chan CT. Newer paradigms in renal replacement therapy: will they alter cardiovascular outcomes? Cardiol Clin 2005; 23(3): 385-91.
[http://dx.doi.org/10.1016/j.ccl.2005.03.001] [PMID: 16084286]
[74]
Charra B. Is there a magic in long nocturnal dialysis? Contrib Nephrol 2005; 149: 100-6.
[http://dx.doi.org/10.1159/000085463] [PMID: 15876833]
[75]
Pierratos A. Daily (quotidian) nocturnal home hemodialysis: nine years later. Hemodial Int 2004; 8(1): 45-50.
[http://dx.doi.org/10.1111/j.1492-7535.2004.00074.x] [PMID: 19379401]
[76]
Bugeja A, Dacouris N, Thomas A, et al. In-center nocturnal hemodialysis: another option in the management of chronic kidney disease. Clin J Am Soc Nephrol 2009; 4(4): 778-83.
[http://dx.doi.org/10.2215/CJN.05221008] [PMID: 19339410]
[77]
Graham-Brown MP, Churchward DR, Smith AC, Baines RJ, Burton JO. A 4-month programme of in-centre nocturnal haemodialysis was associated with improvements in patient outcomes. Clin Kidney J 2015; 8(6): 789-95.
[http://dx.doi.org/10.1093/ckj/sfv096] [PMID: 26613041]
[78]
Thumfart J, Pommer W, Querfeld U, Müller D. Intensified hemodialysis in adults, and in children and adolescents. Dtsch Arztebl Int 2014; 111(14): 237-43.
[http://dx.doi.org/10.3238/arztebl.2014.0237] [PMID: 24766711]
[79]
Walsh M, Culleton B, Tonelli M, Manns B. A systematic review of the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Kidney Int 2005; 67(4): 1500-8.
[http://dx.doi.org/10.1111/j.1523-1755.2005.00228.x] [PMID: 15780103]
[80]
Kotanko P, Garg AX, Depner T, et al. Effects of frequent hemodialysis on blood pressure: Results from the randomized frequent he-modialysis network trials. Hemodial Int 2015; 19(3): 386-401.
[http://dx.doi.org/10.1111/hdi.12255] [PMID: 25560227]
[81]
Chan CT, Harvey PJ, Picton P, Pierratos A, Miller JA, Floras JS. Short-term blood pressure, noradrenergic, and vascular effects of nocturnal home hemodialysis. Hypertension 2003; 42(5): 925-31.
[http://dx.doi.org/10.1161/01.HYP.0000097605.35343.64] [PMID: 14557284]
[82]
Nesrallah G, Suri R, Moist L, Kortas C, Lindsay RM. Volume control and blood pressure management in patients undergoing quotidian hemodialysis. Am J Kidney Dis 2003; 42(1)(Suppl.): 13-7.
[http://dx.doi.org/10.1016/S0272-6386(03)00532-8] [PMID: 12830438]
[83]
Demirci MS, Celik G, Ozkahya M, et al. Effects of thrice weekly nocturnal hemodialysis on arterial stiffness. Atherosclerosis 2012; 220(2): 477-85.
[http://dx.doi.org/10.1016/j.atherosclerosis.2011.11.015] [PMID: 22172590]
[84]
Kalirao P, Kaplan JM. Nocturnal hemodialysis. Clin Exp Nephrol 2009; 13(4): 257-62.
[http://dx.doi.org/10.1007/s10157-008-0110-1] [PMID: 19153805]
[85]
Chan CT, Hanly P, Gabor J, Picton P, Pierratos A, Floras JS. Impact of nocturnal hemodialysis on the variability of heart rate and duration of hypoxemia during sleep. Kidney Int 2004; 65(2): 661-5.
[http://dx.doi.org/10.1111/j.1523-1755.2004.00384.x] [PMID: 14717939]
[86]
Budhiraja R, Budhiraja P, Quan SF. Sleep-disordered breathing and cardiovascular disorders. Respir Care 2010; 55(10): 1322-32.
[PMID: 20875159]
[87]
Chan CT, Jain V, Picton P, Pierratos A, Floras JS. Nocturnal hemodialysis increases arterial baroreflex sensitivity and compliance and normalizes blood pressure of hypertensive patients with end-stage renal disease. Kidney Int 2005; 68(1): 338-44.
[http://dx.doi.org/10.1111/j.1523-1755.2005.00411.x] [PMID: 15954925]
[88]
Huang JT, Cheng HM, Yu WC, Lin YP, Sung SH, Chen CH. Increased nighttime pulse pressure variability but not ambulatory blood pressure levels predicts 14-year all-cause mortality in patients on hemodialysis. Hypertension 2019; 74(3): 660-8.
[http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13204] [PMID: 31352830]
[89]
Ranpuria R, Hall M, Chan CT, Unruh M. Heart rate variability (HRV) in kidney failure: measurement and consequences of reduced HRV. Nephrol Dial Transplant 2008; 23(2): 444-9.
[http://dx.doi.org/10.1093/ndt/gfm634] [PMID: 18003665]
[90]
Kuo G, Chen SW, Huang JY, et al. Short-term heart rate variability as a predictor of long-term survival in patients with chronic hemodialysis: A prospective cohort study. J Formos Med Assoc 2018; 117(12): 1058-64.
[http://dx.doi.org/10.1016/j.jfma.2018.09.006] [PMID: 30293929]
[91]
Smith AL, Owen H, Reynolds KJ. Heart rate variability indices for very short-term (30 beat) analysis. Part 2: validation. J Clin Monit Comput 2013; 27(5): 577-85.
[http://dx.doi.org/10.1007/s10877-013-9473-2] [PMID: 23681923]
[92]
Chou YH, Tsai TJ. Autonomic dysfunction in chronic kidney disease: An old problem in a new era. J Formos Med Assoc 2016; 115(9): 687-8.
[http://dx.doi.org/10.1016/j.jfma.2016.04.008] [PMID: 27375046]
[93]
Ferrario M, Raimann JG, Larive B, et al. Non-linear heart rate variability indices in the frequent hemodialysis network trials of chronic hemodialysis patients. Blood Purif 2015; 40(1): 99-108.
[http://dx.doi.org/10.1159/000381665] [PMID: 26159747]
[94]
Vita G, Bellinghieri G, Trusso A, et al. Uremic autonomic neuropathy studied by spectral analysis of heart rate. Kidney Int 1999; 56(1): 232-7.
[http://dx.doi.org/10.1046/j.1523-1755.1999.00511.x] [PMID: 10411697]
[95]
Chen SC, Huang JC, Tsai YC, et al. Heart rate variability change before and after hemodialysis is associated with overall and cardio-vascular mortality in hemodialysis. Sci Rep 2016; 6: 20597.
[http://dx.doi.org/10.1038/srep20597] [PMID: 26854202]
[96]
Chandra P, Sands RL, Gillespie BW, et al. Predictors of heart rate variability and its prognostic significance in chronic kidney disease. Nephrol Dial Transplant 2012; 27(2): 700-9.
[http://dx.doi.org/10.1093/ndt/gfr340] [PMID: 21765187]
[97]
Drawz PE, Babineau DC, Brecklin C, et al. Heart rate variability is a predictor of mortality in chronic kidney disease: a report from the CRIC Study. Am J Nephrol 2013; 38(6): 517-28.
[http://dx.doi.org/10.1159/000357200] [PMID: 24356377]
[98]
Brotman DJ, Bash LD, Qayyum R, et al. Heart rate variability predicts ESRD and CKD-related hospitalization. J Am Soc Nephrol 2010; 21(9): 1560-70.
[http://dx.doi.org/10.1681/ASN.2009111112] [PMID: 20616169]
[99]
Chan CT. Heart rate variability in patients with end-stage renal disease: An emerging predictive tool for sudden cardiac death? Nephrol Dial Transplant 2008; 23(10): 3061-2.
[http://dx.doi.org/10.1093/ndt/gfn280] [PMID: 18503010]
[100]
Nishimura M, Hashimoto T, Kobayashi H, et al. Association between cardiovascular autonomic neuropathy and left ventricular hy-pertrophy in diabetic haemodialysis patients. Nephrol Dial Transplant 2004; 19(10): 2532-8.
[http://dx.doi.org/10.1093/ndt/gfh361] [PMID: 15252162]
[101]
Zoccali C, Mallamaci F, Parlongo S, et al. Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease. Circulation 2002; 105(11): 1354-9.
[http://dx.doi.org/10.1161/hc1102.105261] [PMID: 11901048]
[102]
Burton JO, Jefferies HJ, Selby NM, McIntyre CW. Hemodialysis-induced repetitive myocardial injury results in global and segmental reduction in systolic cardiac function. Clin J Am Soc Nephrol 2009; 4(12): 1925-31.
[http://dx.doi.org/10.2215/CJN.04470709] [PMID: 19808220]
[103]
Oikawa K, Ishihara R, Maeda T, et al. Prognostic value of heart rate variability in patients with renal failure on hemodialysis. Int J Cardiol 2009; 131(3): 370-7.
[http://dx.doi.org/10.1016/j.ijcard.2007.10.033] [PMID: 18199499]
[104]
Chan CT, Chertow GM, Daugirdas JT, et al. Effects of daily hemodialysis on heart rate variability: results from the frequent hemodialysis network (FHN) daily trial. Nephrol Dial Transplant 2014; 29(1): 168-78.
[http://dx.doi.org/10.1093/ndt/gft212] [PMID: 24078335]
[105]
Zilch O, Vos PF, Oey PL, et al. Sympathetic hyperactivity in haemodialysis patients is reduced by short daily haemodialysis. J Hypertens 2007; 25(6): 1285-9.
[http://dx.doi.org/10.1097/HJH.0b013e3280f9df85] [PMID: 17563543]
[106]
Chertow GM, Levin NW, Beck GJ, et al. Long-term effects of frequent in-center hemodialysis. J Am Soc Nephrol 2016; 27(6): 1830-6.
[http://dx.doi.org/10.1681/ASN.2015040426] [PMID: 26467779]
[107]
Thomson BK, Huang SH, Chan C, Urquhart B, Skanes A, Lindsay RM. Nocturnal home hemodialysis associates with improvement of electrocardiographic features linked to sudden cardiac death. ASAIO J 2014; 60(1): 99-105.
[http://dx.doi.org/10.1097/MAT.0000000000000023] [PMID: 24335385]
[108]
Shimizu M, Ino H, Okeie K, et al. T-peak to T-end interval may be a better predictor of high-risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin I mutation than QT dispersion. Clin Cardiol 2002; 25(7): 335-9.
[http://dx.doi.org/10.1002/clc.4950250706] [PMID: 12109867]
[109]
Watanabe N, Kobayashi Y, Tanno K, et al. Transmural dispersion of repolarization and ventricular tachyarrhythmias. J Electrocardiol 2004; 37(3): 191-200.
[http://dx.doi.org/10.1016/j.jelectrocard.2004.02.002] [PMID: 15286932]
[110]
Thomson BK, Momciu B, Huang SH, et al. Frequent nocturnal hemodialysis associates with improvement of prolonged QTc intervals. Nephron Clin Pract 2013; 123(1-2): 74-82.
[http://dx.doi.org/10.1159/000351382] [PMID: 23860412]
[111]
Bleyer AJ, Hartman J, Brannon PC, Reeves-Daniel A, Satko SG, Russell G. Characteristics of sudden death in hemodialysis patients. Kidney Int 2006; 69(12): 2268-73.
[http://dx.doi.org/10.1038/sj.ki.5000446] [PMID: 16672908]
[112]
Ganesh SK, Stack AG, Levin NW, Hulbert-Shearon T, Port FK. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 2001; 12(10): 2131-8.
[PMID: 11562412]
[113]
Hanly PJ, Pierratos A. Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med 2001; 344(2): 102-7.
[http://dx.doi.org/10.1056/NEJM200101113440204] [PMID: 11150360]
[114]
Kimmel PL, Miller G, Mendelson WB. Sleep apnea syndrome in chronic renal disease. Am J Med 1989; 86(3): 308-14.
[http://dx.doi.org/10.1016/0002-9343(89)90301-X] [PMID: 2919612]
[115]
Hanly P. Sleep disorders and home dialysis. Adv Chronic Kidney Dis 2009; 16(3): 179-88.
[http://dx.doi.org/10.1053/j.ackd.2009.02.004] [PMID: 19393968]
[116]
Lyons OD, Inami T, Perger E, Yadollahi A, Chan CT, Bradley TD. The effect of fluid overload on sleep apnoea severity in haemodialysis patients. Eur Respir J 2017; 49(4)1601789
[http://dx.doi.org/10.1183/13993003.01789-2016] [PMID: 28381432]
[117]
Unruh ML. Sleep apnea and dialysis therapies: things that go bump in the night? Hemodial Int 2007; 11(4): 369-78.
[http://dx.doi.org/10.1111/j.1542-4758.2007.00203.x] [PMID: 17922730]
[118]
Zoccali C, Mallamaci F, Tripepi G. Nocturnal hypoxemia: a neglected cardiovascular risk factor in end-stage renal disease? Blood Purif 2002; 20(1): 120-3.
[http://dx.doi.org/10.1159/000046995] [PMID: 11803169]
[119]
Shiota S, Ryan CM, Chiu KL, et al. Alterations in upper airway cross-sectional area in response to lower body positive pressure in healthy subjects. Thorax 2007; 62(10): 868-72.
[http://dx.doi.org/10.1136/thx.2006.071183] [PMID: 17442706]
[120]
Chiu KL, Ryan CM, Shiota S, et al. Fluid shift by lower body positive pressure increases pharyngeal resistance in healthy subjects. Am J Respir Crit Care Med 2006; 174(12): 1378-83.
[http://dx.doi.org/10.1164/rccm.200607-927OC] [PMID: 16998093]
[121]
Beecroft JM, Hoffstein V, Pierratos A, Chan CT, McFarlane P, Hanly PJ. Nocturnal haemodialysis increases pharyngeal size in patients with sleep apnoea and end-stage renal disease. Nephrol Dial Transplant 2008; 23(2): 673-9.
[http://dx.doi.org/10.1093/ndt/gfm598] [PMID: 17890744]
[122]
Orr JE, Malhotra A, Sands SA. Pathogenesis of central and complex sleep apnoea. Respirology 2017; 22(1): 43-52.
[http://dx.doi.org/10.1111/resp.12927] [PMID: 27797160]
[123]
Beecroft JM, Duffin J, Pierratos A, Chan CT, McFarlane P, Hanly PJ. Decreased chemosensitivity and improvement of sleep apnea by nocturnal hemodialysis. Sleep Med 2009; 10(1): 47-54.
[http://dx.doi.org/10.1016/j.sleep.2007.11.017] [PMID: 18226958]
[124]
Pletcher MJ, Tice JA, Pignone M, Browner WS. Using the coronary artery calcium score to predict coronary heart disease events: a sys-tematic review and meta-analysis. Arch Intern Med 2004; 164(12): 1285-92.
[http://dx.doi.org/10.1001/archinte.164.12.1285] [PMID: 15226161]
[125]
Huybrechts KF, Caro JJ, London GM. Modeling the implications of changes in vascular calcification in patients on hemodialysis. Kidney Int 2005; 67(4): 1532-8.
[http://dx.doi.org/10.1111/j.1523-1755.2005.00233.x] [PMID: 15780108]
[126]
Pierratos A, McFarlane P, Chan CT, Kwok S, Nesrallah G. Daily hemodialysis 2006. State of the art. Minerva Urol Nefrol 2006; 58(2): 99-115.
[PMID: 16767065]
[127]
Kim SJ, Goldstein M, Szabo T, Pierratos A. Resolution of massive uremic tumoral calcinosis with daily nocturnal home hemodialysis. Am J Kidney Dis 2003; 41(3)E12
[http://dx.doi.org/10.1053/ajkd.2003.50139] [PMID: 12613005]
[128]
Yuen D, Pierratos A, Richardson RM, Chan CT. The natural history of coronary calcification progression in a cohort of nocturnal haemodialysis patients. Nephrol Dial Transplant 2006; 21(5): 1407-12.
[http://dx.doi.org/10.1093/ndt/gfl021] [PMID: 16504981]
[129]
Moe SM, O’Neill KD, Reslerova M, Fineberg N, Persohn S, Meyer CA. Natural history of vascular calcification in dialysis and transplant patients. Nephrol Dial Transplant 2004; 19(9): 2387-93.
[http://dx.doi.org/10.1093/ndt/gfh303] [PMID: 15252163]
[130]
Van Eps CL, Jeffries JK, Anderson JA, et al. Mineral metabolism, bone histomorphometry and vascular calcification in alternate night nocturnal haemodialysis. Nephrology (Carlton) 2007; 12(3): 224-33.
[http://dx.doi.org/10.1111/j.1440-1797.2006.00712.x] [PMID: 17498116]
[131]
Chan CT, Harvey PJ, Böger R, Pierratos A, Floras JS. Dissociation between the short-term effects of nocturnal hemodialysis on endothelium dependent vasodilation and plasma ADMA. Arterioscler Thromb Vasc Biol 2005; 25(12): 2685-6.
[http://dx.doi.org/10.1161/01.ATV.0000193890.94720.1a] [PMID: 16306437]
[132]
Schnabel R, Blankenberg S, Lubos E, et al. Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study. Circ Res 2005; 97(5): e53-9.
[http://dx.doi.org/10.1161/01.RES.0000181286.44222.61] [PMID: 16100045]
[133]
Passauer J, Pistrosch F, Büssemaker E, Lässig G, Herbrig K, Gross P. Reduced agonist-induced endothelium-dependent vasodilation in uremia is attributable to an impairment of vascular nitric oxide. J Am Soc Nephrol 2005; 16(4): 959-65.
[http://dx.doi.org/10.1681/ASN.2004070582] [PMID: 15728785]
[134]
Vallance P, Leiper J. Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol 2004; 24(6): 1023-30.
[http://dx.doi.org/10.1161/01.ATV.0000128897.54893.26] [PMID: 15105281]
[135]
Sen S, McDonald SP, Coates PT, Bonder CS. Endothelial progenitor cells: novel biomarker and promising cell therapy for cardiovascular disease. Clin Sci (Lond) 2011; 120(7): 263-83.
[http://dx.doi.org/10.1042/CS20100429] [PMID: 21143202]
[136]
Pauly RP, Chan CT. Reversing the risk factor paradox: is daily nocturnal hemodialysis the solution? Semin Dial 2007; 20(6): 539-43.
[http://dx.doi.org/10.1111/j.1525-139X.2007.00344.x] [PMID: 17991201]
[137]
Szmitko PE, Fedak PW, Weisel RD, Stewart DJ, Kutryk MJ, Verma S. Endothelial progenitor cells: new hope for a broken heart. Circulation 2003; 107(24): 3093-100.
[http://dx.doi.org/10.1161/01.CIR.0000074242.66719.4A] [PMID: 12821589]
[138]
Verma S, Kuliszewski MA, Li SH, et al. C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation 2004; 109(17): 2058-67.
[http://dx.doi.org/10.1161/01.CIR.0000127577.63323.24] [PMID: 15078802]
[139]
Chan CT, Li SH, Verma S. Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease. Am J Physiol Renal Physiol 2005; 289(4): F679-84.
[http://dx.doi.org/10.1152/ajprenal.00127.2005] [PMID: 15928211]
[140]
Roumeliotis S, Dounousi E, Eleftheriadis T, Liakopoulos V. Association of the inactive circulating matrix gla protein with vitamin k intake, calcification, mortality, and cardiovascular disease: a review. Int J Mol Sci 2019; 20(3)E628
[http://dx.doi.org/10.3390/ijms20030628] [PMID: 30717170]
[141]
Block GA, Hulbert-Shearon TE, Levin NW, Port FK. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study. Am J Kidney Dis 1998; 31(4): 607-17.
[http://dx.doi.org/10.1053/ajkd.1998.v31.pm9531176] [PMID: 9531176]
[142]
Mucsi I, Hercz G, Uldall R, Ouwendyk M, Francoeur R, Pierratos A. Control of serum phosphate without any phosphate binders in patients treated with nocturnal hemodialysis. Kidney Int 1998; 53(5): 1399-404.
[http://dx.doi.org/10.1046/j.1523-1755.1998.00875.x] [PMID: 9573558]
[143]
Lindsay RM, Alhejaili F, Nesrallah G, et al. Calcium and phosphate balance with quotidian hemodialysis. Am J Kidney Dis 2003; 42(1)(Suppl.): 24-9.
[http://dx.doi.org/10.1016/S0272-6386(03)00534-1] [PMID: 12830440]
[144]
Daugirdas JT, Chertow GM, Larive B, et al. Effects of frequent hemodialysis on measures of CKD mineral and bone disorder. J Am Soc Nephrol 2012; 23(4): 727-38.
[http://dx.doi.org/10.1681/ASN.2011070688] [PMID: 22362907]
[145]
Al-Hejaili F, Kortas C, Leitch R, et al. Nocturnal but not short hours quotidian hemodialysis requires an elevated dialysate calcium concentration. J Am Soc Nephrol 2003; 14(9): 2322-8.
[http://dx.doi.org/10.1097/01.ASN.0000083044.42480.C1] [PMID: 12937309]
[146]
Stark GR. Reactions of cyanate with functional groups of proteins. 3. Reactions with amino and carboxyl groups. Biochemistry 1965; 4(6): 1030-6.
[http://dx.doi.org/10.1021/bi00882a008] [PMID: 5839993]
[147]
Kalim S, Karumanchi SA, Thadhani RI, Berg AH. Protein carbamylation in kidney disease: pathogenesis and clinical implications. Am J Kidney Dis 2014; 64(5): 793-803.
[http://dx.doi.org/10.1053/j.ajkd.2014.04.034] [PMID: 25037561]
[148]
El-Gamal D, Rao SP, Holzer M, et al. The urea decomposition product cyanate promotes endothelial dysfunction. Kidney Int 2014; 86(5): 923-31.
[http://dx.doi.org/10.1038/ki.2014.218] [PMID: 24940796]
[149]
Berg AH, Drechsler C, Wenger J, et al. Carbamylation of serum albumin as a risk factor for mortality in patients with kidney failure. Sci Transl Med 2013; 5(175)175ra29
[http://dx.doi.org/10.1126/scitranslmed.3005218] [PMID: 23467560]
[150]
Drechsler C, Kalim S, Wenger JB, et al. Protein carbamylation is associated with heart failure and mortality in diabetic patients with end-stage renal disease. Kidney Int 2015; 87(6): 1201-8.
[http://dx.doi.org/10.1038/ki.2014.429] [PMID: 25671766]
[151]
Kalim S, Ortiz G, Trottier CA, et al. The effects of parenteral amino acid therapy on protein carbamylation in maintenance hemodialysis patients. J Ren Nutr 2015; 25(4): 388-92.
[http://dx.doi.org/10.1053/j.jrn.2015.01.019] [PMID: 25753604]
[152]
Perl J, Kalim S, Wald R, et al. Reduction of carbamylated albumin by extended hemodialysis. Hemodial Int 2016; 20(4): 510-21.
[http://dx.doi.org/10.1111/hdi.12435] [PMID: 27329430]
[153]
Chan CT. Nocturnal hemodialysis: an attempt to correct the “unphysiology” of conventional intermittent renal replacement therapy. Clin Invest Med 2002; 25(6): 233-5.
[PMID: 12516993]

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