This paper includes different analytical methods available for the estimation of the Perindopril
Erbumine. Perindopril Erbumine is an Angiotensin-Converting Enzyme (ACE) inhibitor used to
treat hypertension and heart failure. The drug is officially listed in the monograph of USP, BP & EP.
This drug is available in various marketed formulations. There are so many methods reported for the
estimation of Perindopril Erbumine and its related substances. Various methods including UVspectroscopic
method, stability-indicating liquid chromatography method, Thermo-Radio, and Photostability
study, Stability indicating UHPLC-DAD method, LC-MS/MS electrospray ionization validated
method, and LC-MS/MS bioanalytical method are discussed in this paper.