Analytical Techniques for the Estimation of Perindopril Erbumine: A Review

Author(s): Khyati Pathak, Mona Kaushal*, Himani Patel

Journal Name: Current Pharmaceutical Analysis

Volume 17 , Issue 2 , 2021

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Graphical Abstract:


This paper includes different analytical methods available for the estimation of the Perindopril Erbumine. Perindopril Erbumine is an Angiotensin-Converting Enzyme (ACE) inhibitor used to treat hypertension and heart failure. The drug is officially listed in the monograph of USP, BP & EP. This drug is available in various marketed formulations. There are so many methods reported for the estimation of Perindopril Erbumine and its related substances. Various methods including UVspectroscopic method, stability-indicating liquid chromatography method, Thermo-Radio, and Photostability study, Stability indicating UHPLC-DAD method, LC-MS/MS electrospray ionization validated method, and LC-MS/MS bioanalytical method are discussed in this paper.

Keywords: Angiotensin-Converting Enzyme Inhibitor (ACE Inhibitor), Ultraviolet High-Performance Liquid Chromatography- Diode Array Detector method (UHPLC-DAD method), Liquid Chromatography-Mass Spectroscopy/Mass Spectroscopy (LC-MS/MS), Perindopril Erbumine, thin layer chromatography, drugs.

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Article Details

Year: 2021
Published on: 25 January, 2021
Page: [185 - 193]
Pages: 9
DOI: 10.2174/1573412916666200327152049
Price: $65

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PDF: 16