Nanotechnology: A Novel Approach for Drug Development in Health Care System

Author(s): Biswa M. Sahoo*, Bera V.V.R. Kumar, Ch. Niranjan Patra, Jnyanaranjan R. Panda, Bibhash C. Mohanta, Narahari N. Palei

Journal Name: Current Nanomaterials

Volume 5 , Issue 1 , 2020

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Graphical Abstract:


Background: Health is a lively state of the body which adjusts and adopt with the response to various environmental changes. There are several features that can influence the health status of human beings. Therefore, the continuous research study is highly essential to maintain a proper health care system in the community.

Objective: The diverse area of innovation was made in nanotechnology for diagnosis and treatment of life-threatening diseases, such as obesity, diabetes, cardiovascular disorders, cancer, leukemia, neurodegenerative disorders like Alzheimer's disease and Parkinson's diseases, etc. Nanotechnology generally refers to the materials, devices, and systems in nanoscale which provides considerably improved physical, chemical and biological property.

Methods: It is technology which deals with the design, synthesis, characterization of substances, devices and systems by arranging shape and size at their nanometer scale. It involves multidisciplinary research which includes both health science and technology for the treatment of human health. Nanotechnology can be applied at the cellular level in the human body with a high degree of specificity to treat the various diseases.

Conclusion: This technology is potentially targeted to diseased tissue to achieve maximum therapeutic efficacy with fewer side effects. Nowadays, the rapidity of revolutionary discoveries in the field of nanotechnology is expected to accelerate in the next decade globally.

Keywords: Nanotechnology, novel approaches, drugs, development, delivery system, diseases, health.

Mohamed AH, Ahmed EL. Health and environmental impacts of dyes: mini review. Am J Environ Sci 2017; 1(3): 64-7.
Rita Kant. Textile dyeing industry an environmental hazard. Nat Sci 2012; 4(1): 22-6.
Puttaswamy, Shubha JP, Jagadeesh RV. Ruthenium(III) - catalyzed oxidative cleavage of p-aminoazobenzene by chloramine-B in alkaline medium and uncatalyzed reaction in acid medium: spectrophotometric kinetic and mechanistic study. Transition Met Chem 2007; 32(7): 991-9.
Shubha JP, Puttaswamy VK. Kinetics and mechanistic chemistry of butacaine sulfate by Chloramine-b in acid medium. Bull Korean Chem Soc 2012; 33(11): 3539-43.
Puttaswamy, Vinod KN, Ninge Gowda. Oxidation of C.I. acid red 27 by Chloramine-T in perchloric acid medium: spectrophotometric, kinetic and mechanistic approaches. Dyes Pigm 2008; 78(2): 131-8.
Depan D, Misra RDK. Structural and physicochemical aspects of silica encapsulated ZnO quantum dots with high quantum yield and their natural uptake in HeLa cells. J Biomed Mater Res A 2014; 102(9): 2934-41.
[] [PMID: 24115677]
Manjunath K, Ravishankar TN, Dhanith K, et al. Facile combustion synthesis of ZnO nanoparticles using Cajanus cajan (L.) and its multidisciplinary applications. Mater Res Bull 2014; 57: 325-34.
Pavithra NS, Lingaraju K, Raghu GK, Nagaraju G. Citrus maxima (Pomelo) juice mediated eco-friendly synthesis of ZnO nanoparticles: Applications to photocatalytic, electrochemical sensor and antibacterial activities. Spectrochim Acta A Mol Biomol Spectrosc 2017; 185: 11-9.
[] [PMID: 28528217]
Nagaraju G, Nagabhushana H, Suresh D, Anupama C, Raghu GK, Sharma SC. Vitis labruska skin extract assisted green synthesis of ZnO super structures for multifunctional applications. Ceram Int 2017; 43(15): 11656-67.
Channei D, Inceesungvorn B, Wetchakun N, et al. Photocatalytic degradation of methyl orange by CeO2 and Fe-doped CeO2 films under visible light irradiation. Sci Rep 2014; 4: 5757.
[] [PMID: 25169653]
Nagaraju G, Manjunath K, Nagabhushana H, Ebeling G, Dupont J. Ionic liquid-assisted hydrothermal synthesis of TiO2 nanoparticles and its application in photocatalysis. J Mater Sci 2013; 48(24): 8420-6.
Udayabhanu NG, Shubha JP, Manjunath K, Dupont J. Ionothermal synthesis of TiO2 nanoparticles for enhanced photocatalytic H2 generation. Int J Hydrogen Energy 2017; 43(8): 4028-35.
Girija K, Thirumalairajan S, Mastelaro VR, Mangalaraj D. Photocatalytic degradation of organic pollutants by shape selective synthesis of β-Ga2O3 microspheres constituted by nanospheres for environmental remediation. J Mater Chem A Mater Energy Sustain 2015; 3: 2617-27.
Safa S, Azimirad R, Safalou SM, Rabbani M. Investigating on photocatalytic performance of CuO micro and nanostructures prepared by different precursors. Desal Water Treat 2016; 57(15): 6723-31.
Anukorn P, Sineenat S, Paweena W, Somchai T, Titipun T. Microwave-assisted synthesis, photocatalysis and antibacterial activity of Ag nanoparticles supported on ZnO flowers. J Phys Chem 2019; 126: 170-7.
Trilok KP, Kroon RE, Swart HC. Photocatalytic and biological applications of Ag and Au doped ZnO nanomaterial synthesized by combustion. Vacuum 2018; 157: 508-13.
Alireza K, Reza DCS, Younes H, Mahdie S, Habib GR, Sang WJ. Synthesis and characterization of dysprosium-doped ZnO nanoparticles for photocatalysis of a textile dye under visible light irradiation. Ind Eng Chem Res 2014; 535: 1924-32.
Carrillo MAH, Ricardez RT, Mendoza MFG, et al. Eu-modified ZnO nanoparticles for applications in photocatalysis. Catal Today In Press
Torres HJR, Morales ER, Rojas BL, et al. Structural, optical and photocatalytic properties of ZnO nanoparticles modified with Cu. Mat Sci Semiconductor 2015; 37: 87-92.
Flores NM, Pal U, Enrique S. Photocatalytic behavior of ZnO and Pt-incorporated ZnO nanoparticles in phenol degradation. Appl Catal A Gen 2011; 394(1-2): 269-75.
Liqiang J, Xiaojun S, Baifu X, Baiqi W, Weimin C, Honggang F. The preparation and characterization of La doped TiO2 nanoparticles and their photocatalytic activity. J Solid State Chem 2004; 177(10): 3375-82.
Narges K, Mohsen B, Roughollah A, Mostafa K. Synthesis of three-dimensional multilayer graphene foam/zno nanorod composites and their photocatalyst application. J Electron Mater 2018; 47(9): 5452-7.
Bharathi P, Harish S, Archana J, et al. Enhanced charge transfer and separation of hierarchical CuO/ZnO composites: The synergistic effect of photocatalysis for the mineralization of organic pollutant in water. Appl Surf Sci 2019; 484: 884-91.
Jianing L, Fei Z, Li Z, et al. Electrospun hollow ZnO/NiO heterostructures with enhanced photocatalytic activity. RSC Advances 2015; 83(5): 67610-6.
Shushu C, Hui L, Yingzi W, Qian M, Ping Y. Porous NiO/ZnO flower like heterostructures consiositing of interlaced nanosheet/particle framework for enhanced photodegradataion of tetracycline. Mater Lett 2019; 252: 219-22.
Yanli L, Guizhi L, Riding M, Congkun D, Pengzhao G. An environment-benign method for the synthesis of p-NiO/n-ZnO heterostructure with excellent performance for gas sensing and photocatalysis. Sens Actuators B Chem 2014; 191: 537-44.
Blanca LMV, Mariesele CR, Jesus ADR, et al. Synthesis and characterization of n-ZnO/p-MnO nanocomposites for the photocatalytic degradation of anthracene. J Photochem Photobiol Chem 2019; 369: 85-96.
Latha P, Prakash K, Karuthapandian S. Enhanced visible light photocatalytic activity of CeO2/alumina nanocomposite: synthesized via facile mixing-calcination method for dye degradation. Adv Powd Tech 2017; 28(11): 2903-13.
Shashi BA, Wun-Rong L, Ting-Che C, Min-Jen T, Chien-Yen C. Fabrication of Fe3O4/ZnO magnetite core shell and its application in photocatalysis using sunlight. Mater Chem Phys 2018; 216: 380-6.
Acayanka E, Duclair SK, Georges YK, Serge N, Samuel L, Peter TN. Synthesis, Characterization and photocatalytic application of TiO2/SnO2 nanocomposite obtained under non-thermal plasma condition at atmospheric pressure. Plasma Chem Plasma Process 2016; 36(3): 799-811.
Wang L, Liu S, Wang Z, Zhou Y, Qin Y, Wang ZL. Piezotronic effect enhanced photocatalysis in strained anisotropic ZnO/TiO2 nanoplatelets via thermal stress. ACS Nano 2016; 10(2): 2636-43.
[] [PMID: 26745209]
Manjunath K, Souza VS, Ramakrishnappa T, Nagaraju G, Scholten JD, Dupont J. Heterojunction CuO-TiO2 nanocomposite synthesis for significant photocatalytic hydrogen production. Mater Res Express 2016; 3(11) 115904
Zhang Z, Ma Y, Bu X, et al. Facile one-step synthesis of TiO2/Ag/SnO2 ternary heterostructures with enhanced visible light photocatalytic activity. Sci Rep 2018; 8(1): 10532.
[] [PMID: 30002407]
Lingampalli SR, Ujjal KG, Rao CNR. Highly efficient photocatalytic hydrogen generation by solution-processed ZnO/Pt/CdS, ZnO/Pt/Cd1−xZnxS and ZnO/Pt/CdS1−xSex hybrid nanostructures. Energy Environ Sci 2013; 6(12): 3589-94.
Tedla H, Isabel D, Tesfahun K, Taddesse AM. Synthesis, characterization and photocatalytic activity of zeolite 2 supported ZnO/Fe2O3/MnO2 nanocomposites. J Environ Chem Eng 2015; 3(3): 1586-91.
Vahid H, Nasser G. Novel ZnO-MnO2-Cu2O triple nanocomposite: facial synthesis, characterization, antibacterial activity and visible light photocatalytic performance for dyes degradation-A comparative study. Mater Res Express 2018; 5(8) 085012
Masao K. Ichiro O Photocatalysis: Science and Technology. Springer: Berlin, Heidelberg: 2010.

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Article Details

Year: 2020
Page: [12 - 25]
Pages: 14
DOI: 10.2174/2405461505666200320152824

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