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Current Pharmaceutical Biotechnology

Editor-in-Chief

ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Review Article

A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets

Author(s): Fatemeh Emadi, Arash Emadi and Ahmad Gholami*

Volume 21, Issue 11, 2020

Page: [1016 - 1027] Pages: 12

DOI: 10.2174/1389201021666200318131422

Price: $65

Abstract

Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on the application of GDs for the delivery of biopharmaceuticals. Also, the pharmacokinetic properties and the advantage of using GDs in pharmaceutics will be reviewed to achieve a comprehensive understanding about the GDs in pharmaceutical sciences.

Keywords: Graphene, pharmacokinetic, protein delivery, biopharmaceuticals, triggered release, biopharmaceutical targeting.

Graphical Abstract
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