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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

Neglected Diseases - New Compounds and Treatments

Author(s): Luciana Scotti* and Marcus T. Scotti

Volume 27, Issue 5, 2020

Page: [659 - 661] Pages: 3

DOI: 10.2174/092986732705200316141940

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[1]
Scotti, L.; Mendonca, F.J.B.; Moura, R.O.; Ribeiro, F.F.; Ishiki, H.; Da Silva, M.; Filho, J.M.B.; Scotti, M.T. Multi-target drugs for neglected diseases. Curr. Pharm. Des., 2016, 22(21), 3135-3163.
[http://dx.doi.org/10.2174/1381612822666160224142552] [PMID: 26907943]
[2]
Kindhauser, M.K. World Health Organization.. Communicable diseases 2002:Global defence against the infectious disease threat; Geneva, 2003.
[3]
Hunt, P. WHO. Neglected diseases: a human rights analysis, TDR/STR/SEB/ST/07.2. 2007.
[4]
Ribeiro, F.F.; Junior, F.; da Silva, M.S.; Scotti, M.T.; Scotti, L. Computational and investigative study of flavonoids active against Trypanosoma cruzi and Leishmania spp. Nat. Prod. Commun., 2015, 10(6), 917-920.
[http://dx.doi.org/10.11772F1934578X1501000630] [PMID: 26197515]
[5]
Scotti, L.; Ishiki, H.; Mendonca, F.J.B.; Da Silva, M.S.; Scotti, M.T. In-silico analyses of natural products on Leishmania enzyme targets. Mini Rev. Med. Chem., 2015, 15(3), 253-269.
[http://dx.doi.org/10.2174/138955751503150312141854] [PMID: 25769973]
[6]
Gilbert, I.H. Drug discovery for neglected diseases: molecular target-based and phenotypic approaches miniperspectives series on phenotypic screening for antiinfective targets. J. Med. Chem., 2013, 56(20), 7719-7726.
[http://dx.doi.org/10.1021%2Fjm400362b] [PMID: 24015767]
[7]
Scotti, L.; Mendonca, F.J.B.; Moreira, D.R.; Mp; da Silva, M.S.; Pitta, I.R.; Scotti, M.T. SAR, QSAR and docking of anticancer flavonoids and variants: a review. Curr. Top. Med. Chem., 2012, 12(24), 2785-2809.
[http://dx.doi.org/10.2174/1568026611212240007] [PMID: 23368103]
[8]
Scotti, L.; Scotti, M.T.; Pasqualoto, K.F.M.; Bolzani, V.D.; Ferreira, E.I. Molecular physicochemical parameters predicting antioxidant activity of Brazilian natural products. Rev. Bras. Farmacogn., 2009, 19(4), 908-913.
[http://dx.doi.org/10.1590/S0102-695X2009000600020]
[9]
Bellera, C.L.; Alberca, L.N.; Sbaraglini, M.L.; Talevi, A. In Silico drug repositioning for chagas disease. Curr. Med. Chem., 2020, 27(5), 662-675.
[http://dx.doi.org/10.2174/0929867326666191016114839] [PMID: 31622200]
[10]
Thomas, C.M.; Timson, D.J. The mechanism of action of praziquantel: can new drugs exploit similar mechanisms? Curr. Med. Chem., 2020, 27(5), 676-696.
[http://dx.doi.org/10.2174/0929867325666180926145537] [PMID: 30259811]
[11]
Halder, A.K.; Cordeiro, M.N.D.S. Advanced in silico methods for the development of anti-leishmaniasis and anti-trypanosomiasis agents. Curr. Med. Chem., 2020, 27(5), 697-718.
[http://dx.doi.org/10.2174/0929867325666181031093702] [PMID: 30378482]
[12]
Hosseini, S.; Munoz-Soto, R.B.; Oliva-Ramirez, J.; Vazquez-Villegas, P.; Aghamohammadi, N.; Rodriguez-Garcia, A.; Martinez-Chapa, S.O. Latest updates in dengue fever therapeutics: natural, marine and synthetic drugs. Curr. Med. Chem., 2020, 27(5), 719-744.
[http://dx.doi.org/10.2174/0929867325666180629124709] [PMID: 2995661]
[13]
de Ávila, M.B.; Bitencourt-Ferreira, G.; de Azevedo, Jr. W.F. Structural basis for inhibition of enoyl-[acyl carrier protein]reductase (InhA) from Mycobacterium tuberculosis. Curr. Med. Chem., 2020, 27(5), 745-759.
[http://dx.doi.org/10.2174/0929867326666181203125229] [PMID: 30501592]
[14]
Melo, R.; Lemos, A.; Preto, A.J.; Bueschell, B.; Matos-Filipe, P.; Barreto, C.; Almeida, J.G.; Silva, R.D.M.; Correia, J.D.G.; Moreira, I. An overview of antiretroviral agents for treating HIV infection in pediatric population. Curr. Med. Chem., 2020, 27(5), 760-794.
[http://dx.doi.org/10.2174/0929867325666180904123549] [PMID: 30182840]
[15]
Scotti, M.T.; Monteiro, A.F.M.; de Oliveira Viana, J.; Junior, F.J.B., ; Ishiki, H.M.; Tchouboun, E.N.; de Araújo, R.S.A.; Scotti, L. Recent theoretical studies concerning important tropical infections. Curr. Med. Chem., 2020, 27(5), 795-834.
[http://dx.doi.org/10.2174/0929867326666190711121418] [PMID: 31296154]

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