A Generic Computer-Assisted Four-Pronged Approach for the Management of Emerging Global Pathogens: Some Comments on COVID-19

Author(s): Subhash C. Basak, Subhabrata Majumdar, Marjan Vracko, Ashesh Nandy, Apurba Bhattacharjee

Journal Name: Current Computer-Aided Drug Design

Volume 16 , Issue 4 , 2020


Become EABM
Become Reviewer
Call for Editor

[1]
Del Rio, C.; Malani, P.N. COVID-19-New insights on a rapidly changing epidemic. JAMA, 2020.
[http://dx.doi.org/10.1001/jama.2020.3072] [PMID: 32108857]
[2]
Coronavirus disease. 2019. (COVID-19) Situation Report - 40 https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200229-sitrep-40-covid-19.pdf?sfvrsn=7203e653_2 (Accessed on 29 February, 2020).
[3]
Wrapp, D.; Wang, N.; Corbett, K.S.; Goldsmith, J.A.; Hsieh, C.L.; Abiona, O.; Graham, B.S.; McLellan, J.S. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science, 2020, 367(6483), 1260-1263.
[http://dx.doi.org/10.1126/science.abb2507] [PMID: 32075877]
[4]
Bai, Y.; Yao, L.; Wei, T.; Tian, F.; Jin, D.Y.; Chen, L.; Wang, M. presumed asymptomatic carrier transmission of COVID-19. JAMA, 2020.
[http://dx.doi.org/10.1001/jama.2020.2565] [PMID: 32083643]
[5]
Basak, S.C.; Bhattacharjee, A.; Nandy, A. Eds.; Zika virus Surveillance, Vaccinology and Anti-Zika Drug Discovery – Computer Assisted Strategies to Combat the MenaceNova Science Publishers, Nova Medicine and Health: New York, NY, 2019.
[6]
Basak, S.C.; Majumdar, S.; Nandy, A.; Roy, P.; Dutta, T.; Vracko, M.; Bhattacharjee, A.K. Computer-Assisted and data driven approaches for surveillance, drug discovery, and vaccine design for the zika virus. Pharmaceuticals (Basel), 2019, 12(4), 157.
[http://dx.doi.org/10.3390/ph12040157] [PMID: 31623241]
[7]
Cao, Z.; Zhang, Q.; Lu, X. Estimating the effective reproduction number of the 2019-nCoV in China, medRxiv 2020.
[8]
Li, Q.; Guan, X.; Wu, P.; Wang, X.; Zhou, L.; Tong, Y.; Ren, R.; Leung, K.S.M.; Lau, E.H.Y.; Wong, J.Y.; Xing, X.; Xiang, N.; Wu, Y.; Li, C.; Chen, Q.; Li, D.; Liu, T.; Zhao, J.; Liu, M.; Tu, W.; Chen, C.; Jin, L.; Yang, R.; Wang, Q.; Zhou, S.; Wang, R.; Liu, H.; Luo, Y.; Liu, Y.; Shao, G.; Li, H.; Tao, Z.; Yang, Y.; Deng, Z.; Liu, B.; Ma, Z.; Zhang, Y.; Shi, G.; Lam, T.T.Y.; Wu, J.T.; Gao, G.F.; Cowling, B.J.; Yang, B.; Leung, G.M.; Feng, Z. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N. Engl. J. Med., 2020, 382(13), 1199-1207.
[http://dx.doi.org/10.1056/NEJMoa2001316] [PMID: 31995857]
[9]
Read, J.M.; Bridgen, J.R.E.; Cummings, D.A.T. Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions medRxiv, 2020.
[10]
Zhao, S.; Lin, Q.; Ran, J.; Musa, S.S.; Yang, G.; Wang, W.; Lou, Y.; Gao, D.; Yang, L.; He, D.; Wang, M.H. Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak. Int. J. Infect. Dis., 2020, 92, 214-217.
[http://dx.doi.org/10.1016/j.ijid.2020.01.050] [PMID: 32007643]
[11]
Vracko, M.; Basak, S.C.; Sen, D.; Nandy, A. Clustering of Zika viruses originating from different geographical regions using computational sequence descriptors, Curr; Comput; Aided Drug Des, 2019.
[12]
Nandy, A.; Basak, S.C. The Wuhan epidemic, 2019. https://www.researchgate.net/publication/338832597_The_Wuhan_epidemic_2019_-A_commentary accessed on 29 February, 2020.
[13]
Paul, S.M.; Mytelka, D.S.; Dunwiddie, C.T.; Persinger, C.C.; Munos, B.H.; Lindborg, S.R.; Schacht, A.L. How to improve R&D productivity: the pharmaceutical industry’s grand challenge. Nat. Rev. Drug Discov., 2010, 9(3), 203-214.
[http://dx.doi.org/10.1038/nrd3078] [PMID: 20168317]
[14]
Bhattacharjee, A.K. Pharmacophore modeling applied to mosquito-borne diseases.Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases; Devillers, J., Ed.; CRC Press: Boca Raton, FL, 2018, pp. 139-169.
[15]
Bhattacharjee, A.K. Discovery of anti-zika drugs using in silico pharmacophore modeling.Zika Virus Surveillance, Vaccinology, and Anti-zika Drug Discovery; ; Basak, S.C.; Bhattacharjee, A.K.; Nandy, A., Eds. Nova: New York, NY, 2019, pp. 39-73.
[16]
Gao, K.; Nguyen, D.D.; Wang, R.; Wei, G-W. Machine intelligence design of 2019-nCoV drugs. bioRxiv, 2020.
[http://dx.doi.org/10.1101/2020.01.30.927889]


free to download

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 16
ISSUE: 4
Year: 2020
Published on: 02 September, 2020
Page: [351 - 353]
Pages: 3
DOI: 10.2174/1573409916999200316102548

Article Metrics

PDF: 40
HTML: 1