Concurrent Methicillin-Resistant Staphylococcus aureus Septicemia and Thyroid Abscess in a Young Male with Dengue

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Author(s): Durga Shankar Meena, Deepak Kumar*, Gopal Krishana Bohra, Mahendra kumar Garg, Naresh Midha, Taruna Yadav, Prakrati Yadav

Journal Name: Infectious Disorders - Drug Targets
(Formerly Current Drug Targets - Infectious Disorders)

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Background: Dengue fever is an arthropod-borne viral infection with a very high incidence in Southeast Asia. Most patients present with self-limiting febrile illness, while some patients may develop complications like acute kidney injury, acute liver failure, myocarditis or Guillain–Barre syndrome. Coexistence of dengue and MRSA (Methicillin-resistant Staphylococcus aureus) is rarely reported in the literature.

Case: We describe a 28-year-old male presented with high-grade fever, polyserositis and thrombocytopenia. The patient was treated symptomatically for dengue infection. During the course of hospitalization, patient developed neck swelling (thyroid abscess) and left forearm abscess. MRSA was isolated from blood culture and pus, and successfully treated with iv antibiotics (Linezolid).

Conclusion: High anticipation and vigilance is required to detect concurrent bacteremia in dengue patients. Early recognition of warning signs with readily antibiotic therapy is important to prevent mortality and morbidity in these patients. Our report also highlights the MRSA as a rare cause of thyroid abscess with only 5 cases have been reported in the literature so far.

Keywords: Dengue, Staphylococcus aureus, Drug Resistance, Thyroid abscess, Coinfection, Thrombocytopenia

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(E-pub Ahead of Print)
DOI: 10.2174/1871526520666200312160701
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