Two Latest Hot Researches in Medicinal Chemistry

Author(s): Guo-Ping Zhou*, Kuo-Chen Chou

Journal Name: Current Topics in Medicinal Chemistry

Volume 20 , Issue 4 , 2020

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Chou, K.C. Advance in predicting subcellular localization of multi-label proteins and its implication for developing multi-target drugs. Curr. Med. Chem., 2019.
Zhou, G.P.; Zhong, W.Z. Perspectives in the medicinal chemistry. Curr. Top. Med. Chem., 2016, 16, 381-382.
Chou, K.C.; Shen, H.B. Recent progresses in protein subcellular location prediction. Anal. Biochem., 2007, 370, 1-16.
Cheng, X.; Xiao, X.; Chou, K.C. pLoc-mEuk: Predict subcellular localization of multi-label eukaryotic proteins by extracting the key GO information into general PseAAC. Genomics, 2018, 110, 50-58.
Liu, B.; Yang, F.; Huang, D-S.; Chou, K.C. iPromoter-2L: a two-layer predictor for identifying promoters and their types by multi-window-based PseKNC. Bioinformatics, 2018, 34(1), 33-40.
Zhou, G.P. Special issue: impacts of biological science to medicinal chemistry. Curr. Top. Med. Chem., 2017, 17, 2335-2336.
Zhou, G.P.; Chen, D.; Liao, S.; Huang, R.B. Recent progresses in studying helix-helix interactions in proteins by incorporating the wenxiang diagram into the nmr spectroscopy. Curr. Top. Med. Chem., 2016, 16, 581-590.
Zhou, G.P.; Huang, R.B. The pH-Triggered Conversion of the PrPc to PrPsc. Curr. Top. Med. Chem., 2013, 13, 1152-1163.
Huang, R.B.; Cheng, D.; Lu, B.; Liao, S.M.; Troy, F.A.; Zhou, G.P. The intrinsic relationship between structure and function of the sialyltransferase st8sia family members. Curr. Top. Med. Chem., 2017, 17, 2359-2369.
Nakata, D.; Zhang, L.; Troy, F.A. Molecular basis for polysialylation: A novel polybasic polysialyltransferase domain (PSTD) of 32 amino acids unique to the α2,8-polysialyltransferases is essential for polysialylation. Glycoconj. J., 2006, 23, 423-436.
Peng, L.X.; Liu, X.H.; Lu, B.; Liao, S.M.; Zhou, F.; Huang, J.M.; Chen, D.; Troy, II F.A.; Zhou, G.P.; Huang, R.B. The inhibition of polysialyltranseferase st8siaiv through heparin binding to polysialyltransferase domain (PSTD). Med. Chem., 2018.
Lu, B.; Liao, S.M.; Liu, X.H.; Lu, Z.L.; Troy, II F.A.; Huang, R.B.; Zhou, G.P. A possible modulation mechanism of intramolecular and intermolecular interactions for ncam polysialylation and cell migration. Curr. Top. Med. Chem., 2019, 19(25), 2271-2282.

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Article Details

Year: 2020
Published on: 26 March, 2020
Page: [264 - 265]
Pages: 2
DOI: 10.2174/156802662004200304124625

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