This article provides comprehensive and collective facts about teneligliptin. Teneligliptin is
a dipeptide peptidase-4 (DPP-4) inhibitor that belongs to the third generation, used in the management
of type 2 diabetes. It inhibits human DPP-4 enzyme activity. This drug falls under class 3; it interacts
with S1, S2, and S2E extensive sub-sites. Teneligliptin and its metabolites are mainly determined in
the human plasma matrix by hyphenated chromatographic methods. These developed methods could
be foreseen for their clinical applications. Moreover, the stress degradation studies of Teneligliptin under
different stress conditions provide an insight into degradation pathways and help in the elucidation
of the structure of the degradation products by liquid mass spectroscopy. These methods are also used
for routine quality control analysis of teneligliptin in pharmaceutical dosage forms.
Keywords: Teneligliptin, identification, pharmacokinetics, pharmacodynamics, chemistry, analysis.
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