Title:A General Method for the Synthesis of 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol-3-yl)(aryl)methanes and tris(indol-3-yl)methanes Using Naturally Occurring Mandelic Acid as an Efficient Organo-catalyst in Aqueous Ethanol at Room Temperature
VOLUME: 7 ISSUE: 1
Author(s):Arvind Singh, Gurpreet Kaur, Amninder Kaur, Vivek K. Gupta and Bubun Banerjee*
Affiliation:Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301, Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301, Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301, Post-Graduate Department of Physics, University of Jammu, Jammu Tawi-180006, Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301
Keywords:bis(indol-3-yl)(aryl)methanes, 3, 3-bis(indol-3-yl)indolin-2-ones, tris(1H-indol-3-yl)methane, mandelic acid, room
temperature, sustainable synthesis.
Abstract:A simple, facile, straightforward and environmentally benign protocol has been developed
for the efficient synthesis of pharmaceutically interesting 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol-
3-yl)(aryl)methanes and tris(indol-3-yl)methanes using a catalytic amount of mandelic acid as an efficient,
naturally occurring, low-cost, commercially available organo-catalyst in aqueous ethanol at
room temperature.