Organic Lesions in the Brain MRI of Children with Febrile Seizure

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Author(s): Alireza Nezami, Fariba Tarhani*, Negin Koochak Shoshtari

Journal Name: Current Medical Imaging
Formerly: Current Medical Imaging Reviews

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Objective: Seizure is the most common neurological disorders in children, where, 4-10% cases experience at least one seizure before the age of 16. The most frequent causes of seizures in children are fever, epilepsy, infection and brain damage. The aim of this study was to investigate the frequency of organic lesions in MRI of children with seizure unrelated to fever.

Materials and Methods: This cross-sectional study included children presented with fever-unrelated seizures. The MRI was examined by a radiologist to identify abnormal findings in each patient. A researcher-made questionnaire including general information, history of head trauma, obstructed labor and the history of seizure were completed for the patients.

Results: Of 287 children with fever-related seizure, 127 (45.7%) were male and 151 (54.3%) were female. History of seizure, history of obstructed labor, abnormal MRI, complete delay, use of antiepileptic drug and history of trauma were 22(9.9%), 1 (0.4%), 11(4%), 5(1.8%), 259(93.2%) and 12 (4.3%) respectively. Of 11 patients with abnormal MRI, 4 had MTS lesions, 2 had tumor lesions, 2 had scarring trauma, 1 had epidural abscess and 1 had meningitis. Frequency of organic lesions had no significant differences based on gender, use of anti-epileptic drug and traumatic history, but it had a significant relation with obstructed labor and the history of seizure.

Conclusion: The results showed that organic brain lesions in children with fever-unrelated seizure, which had a significant relation with the history of seizure and obstructed maternal labor.

Keywords: MRI, organic lesions, fever-unrelated seizure, children, neurological disorder, epilepsy.

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(E-pub Ahead of Print)
DOI: 10.2174/1573405616666200226103615
Price: $95

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