GRASP55: A Multifunctional Protein

Author(s): Hongrong Wu, Tianjiao Li, Jianfeng Zhao*

Journal Name: Current Protein & Peptide Science

Volume 21 , Issue 6 , 2020

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Graphical Abstract:


GRASP55 was first found as Golgi cisternae stacking protein. Due to the crucial role of Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two aspects. Further investigation revealed that GRASP55 also participates in the unconventional secretory pathway under stress. Moreover, GRASP55 is involved in autophagy initiation and autophagosome maturation, as well as cell activity.

Keywords: GRASP55, Golgi, Autophagy, Unconventional secretory pathway, Vesicular trafficking, Golgin45.

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Year: 2020
Published on: 20 August, 2020
Page: [544 - 552]
Pages: 9
DOI: 10.2174/1389203721666200218105302
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