GRASP55 was first found as Golgi cisternae stacking protein. Due to the crucial role of
Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two
aspects. Further investigation revealed that GRASP55 also participates in the unconventional secretory
pathway under stress. Moreover, GRASP55 is involved in autophagy initiation and autophagosome
maturation, as well as cell activity.
Keywords: GRASP55, Golgi, Autophagy, Unconventional secretory pathway, Vesicular trafficking, Golgin45.
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