Title:Bench-to-Bedside Theranostics in Nuclear Medicine
VOLUME: 26 ISSUE: 31
Author(s):Narges Jokar, Majid Assadi, Anna Yordanova and Hojjat Ahmadzadehfar*
Affiliation:The Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, School of Medicine, Bushehr University of Medical Sciences, Bushehr, The Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Department of Nuclear Medicine, University Hospital Bonn, Bonn, Department of Nuclear Medicine, University Hospital Bonn, Bonn
Keywords:Theranostics, precision medicine, MIBG, FAPI, PRRT, PSMA, radioiodine.
Abstract:The optimum selection of the appropriate radiolabelled probe for the right target and the right patient is
the foundation of theranostics in personalised medicine. In nuclear medicine, this process is realised through the
appropriate choice of radiopharmaceuticals based on molecular biomarkers regarding molecular imaging. Theranostics
is developing a strategy that can be used to implement accepted tools for individual molecular targeting,
including diagnostics, and advances in genomic molecular knowledge, which has led to identifying theranostics
biomaterials that have the potency to diagnose and treat malignancies. Today, numerous studies have reported on
the discovery and execution of these radiotracers in personalised medicine. In this review, we presented our point
of view of the most important theranostics agents that can be used to treat several types of malignancies. Molecular
targeted radionuclide treatment methods based on theranostics are excellent paradigms of the relationship
between molecular imaging and therapy that has been used to provide individualised or personalised patient care.
Toward that end, a precise planned prospective examination of theranostics must be done to compare this approach
to more standard therapies.