A catalyst system derived from commercially available Cu(NO3)2.3H2O and 2,5-
dihydroxyterephthalic acid is applied to the homocoupling reaction of arylboronic acids. This transformation
provides a convenient approach to symmetrical biaryls with good to excellent yields (39%-
95%), and exhibits good functional group compatibility. Furthermore, biaryl can be prepared in gram
quantities in good yield.
Keywords: Arylboronic acid, biaryl, ligand, copper, homocoupling reaction, acid.
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