Title:Long-term Effects of Gastric Bypass Surgery in Patients with Obstructive Sleep Apnea
VOLUME: 16 ISSUE: 1
Author(s):Nathir Obeidat, Saif Aldeen AlRyalat*, Khaled Al Oweidat, Mahmoud Abu-Khalaf, Asma Btoush, Mohammad Al-Essa, Zaina Obeidat, Mohammed Obeidat and Ayman Wahbeh
Affiliation:Department of Respiratory and Sleep Medicine, The University of Jordan, Amman, Department of Ophthalmology, The University of Jordan, Amman, Department of Respiratory and Sleep Medicine, The University of Jordan, Amman, Department of Bariatric Surgery, The University of Jordan, Amman, Department of Internal Medicine, The University of Jordan, Amman, Department of Internal Medicine, The University of Jordan, Amman, Department of Internal Medicine, The University of Jordan, Amman, Department of Internal Medicine, The University of Jordan, Amman, Department of Internal Medicine, The University of Jordan, Amman
Keywords:Bariatric surgery, Jordan, obstructive sleep apnea, roux-en-Y gastric bypass, sleep-disordered breathing,
postoperative assessment.
Abstract:
Background: Obstructive sleep apnea is a common disorder involving, intermittent
mechanical obstruction of the upper airway during sleep. Obesity is the most powerful risk factor for
obstructive sleep apnea.
Objective: This study aimed to investigate the long-term effect of Roux-en-Y gastric bypass bariatric
surgery on patients with obstructive sleep apnea.
Methods: This study included patients were referred for bariatric surgery (Roux-en-Y gastric bypass)
to control symptoms and complications of obesity during a 5-year period. An overnight sleep study
was performed for each patient before and after the bariatric surgery, to study its effect on different
obstructive sleep apnea-related variables.
Results: This study included 179 patients (mean age 35.9 ± 10.7 years). The mean duration from preoperative
assessment to postoperative assessment was 2.4 ± 2.2 years. The mean change in body
mass index and weight showed a decrease of 16.0 ± 16.0 kg/m2 and48.7 ± 25.9 kg, respectively. The
apnea hypopnea index decreased by a mean of 22.6 ± 26.3 events/hour.
Conclusion: We concluded that a decrease in the body mass index by 1 kg/m2 could predict a
decrease in the apnea hypopnea index by 0.46 events/hour. Moreover, after mean follow-up duration
of 2.4 years, 84.3% of mild and 83.3% of moderate obstructive sleep apnea patients became normal
postoperatively.