Background: Impacted teeth are commonly asymptomatic and not associated with any
pathologic lesions for years. Any change in the size of the follicle associated with impacted teeth
may result in odontogenic cysts or tumors. CBCT plays an important role in determining the radiographic
features of a lesion and therefore, is very helpful for accurate diagnosis and treatment
Objective: This study aims to evaluate radiolucent lesions associated with impacted teeth in terms
of age and sex distribution, localization, and comparison with the pathological diagnosis.
Methods: In this retrospective study, out of 6758 CBCT images, 400 images revealing radiolucent
lesions were detected. The study included only 190 cases (regarding 180 patients) which had a
matching histopathological evaluation. Data related to the age and sex of the patients, localization
of the lesions, and their comparison with the pathological diagnosis were recorded and analyzed.
Results: The most encountered lesions were dentigerous cysts (60%) and odontogenic keratocysts
(26.3%). Males were the most affected (63.3%). Most of the lesions were found in the left and
right posterior mandible and mostly (66.8 %) associated with third molars. Out of 123 radiological
diagnoses of dentigerous cyst cases, histopathological diagnoses confirmed 108 cases. Regarding
odontogenic keratocyst, histopathological diagnosis confirmed 40 cases out of 48.
Conclusion: Radiological diagnoses of the lesions mostly match with their pathological diagnosis
unless their characteristics are changed due to infection. CBCT, as a technique enabling detailed
imaging of the involved dental structures, is a helpful instrument for differential diagnosis.