Reduce Disease Burden of Human Schistosomiasis in Asia Through Biological Control

Author(s): Sidra Saleem, Haroon Ahmed, Tooba Siddiqui, Seyma Gunyakti Kilinc, Aisha Khan, Muhammad Sohail Afzal, Sami Simsek*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 20 , Issue 12 , 2020


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Abstract:

Schistosomiasis is a chronic parasitic disease caused by a trematode blood fluke of the genus Schistosoma that belongs to the Schistosomatidae family. It is a neglected disease in different regions of Asia. In this review, 218 articles (between 2000 and 2017) related to the topic were collected from PubMed and Google scholar and reviewed. After thoroughly reading collected articles, due to irrelevant topic requirements, 94 articles were excluded. Articles that have data associated with Asian regions are considered. In Asia, the disease is prevalent in China, Philippines, Indonesia, Yemen, Nepal and Laos, etc. While in Pakistan, India and Bangladesh, the disease is not endemic and very few cases were reported. The disease was eliminated from Japan and Iran. The current review highlights the geographical distribution among Asian countries, transmission patterns, diagnosis, control strategies based on the use of anthelmintic plants and management practices implemented in Asia for the control of schistosomiasis. However, new implementations to treat schistosomiasis in humans should be proved to eliminate the disease finally in the future. This review emphasizes the biological control of schistosomiasis for the eradication of the disease from Asia in the near future.

Keywords: Schistosomiasis, distribution, Asia, plants, biological control.

[1]
Colley, D.G.; Bustinduy, A.L.; Secor, W.E.; King, C.H. Human schistosomiasis. Lancet, 2014, 383(9936), 2253-2264.
[http://dx.doi.org/10.1016/S0140-6736(13)61949-2] [PMID: 24698483]
[2]
World Health Organization (WHO). Investing to Overcome the Global Impact of Neglected Tropical Diseases: Third Who Report on Neglected Tropical Diseases 2015.
[3]
World Health Organization (WHO). Schistosomiasis: progress report 2001-2011, strategic plan 2013, 2012-2020.
[4]
Inobaya, M.T.; Olveda, R.M.; Chau, T.N.; Olveda, D.U.; Ross, A.G. Prevention and control of schistosomiasis: a current perspective. Res. Rep. Trop. Med., 2014, 2014(5), 65-75.
[PMID: 25400499]
[5]
Burke, M.L.; Jones, M.K.; Gobert, G.N.; Li, Y.S.; Ellis, M.K.; McManus, D.P. Immunopathogenesis of human schistosomiasis. Parasite Immunol., 2009, 31(4), 163-176.
[http://dx.doi.org/10.1111/j.1365-3024.2009.01098.x] [PMID: 19292768]
[6]
Gauffre-Autelin, P.; von Rintelen, T.; Stelbrink, B.; Albrecht, C. Recent range expansion of an intermediate host for animal schistosome parasites in the Indo-Australian Archipelago: phylogeography of the freshwater gastropod Indoplanorbis exustus in South and Southeast Asia. Parasit. Vectors, 2017, 10(1), 126.
[http://dx.doi.org/10.1186/s13071-017-2043-6] [PMID: 28264699]
[7]
Stanton, M.C.; Adriko, M.; Arinaitwe, M.; Howell, A.; Davies, J.; Allison, G.; LaCourse, E.J.; Muheki, E.; Kabatereine, N.B.; Stothard, J.R. Intestinal schistosomiasis in Uganda at high altitude (>1400 m): malacological and epidemiological surveys on Mount Elgon and in Fort Portal crater lakes reveal extra preventive chemotherapy needs. Infect. Dis. Poverty, 2017, 6(1), 34.
[http://dx.doi.org/10.1186/s40249-017-0248-8] [PMID: 28162096]
[8]
Mewabo, A.P.; Moyou, R.S.; Kouemeni, L.E.; Ngogang, J.Y.; Kaptue, L.; Tambo, E. Assessing the prevalence of urogenital schistosomaisis and transmission risk factors amongst school-aged children around Mapé dam ecological suburbs in Malantouen district, Cameroon. Infect. Dis. Poverty, 2017, 6(1), 40.
[http://dx.doi.org/10.1186/s40249-017-0257-7] [PMID: 28260525]
[9]
Olveda, D.U.; Li, Y.; Olveda, R.M.; Lam, A.K.; McManus, D.P.; Chau, T.N.; Harn, D.A.; Williams, G.M.; Gray, D.J.; Ross, A.G. Bilharzia in the Philippines: past, present, and future. Int. J. Infect. Dis., 2014, 18, 52-56.
[http://dx.doi.org/10.1016/j.ijid.2013.09.011] [PMID: 24211228]
[10]
El-Shahawy, I.; Khalil, M.; Adail, A. Some epidemiological and serological studies on schistosomiasis in Najran area, Saudi Arabia. Helminthol., 2016, 53, 172-179.
[http://dx.doi.org/10.1515/helmin-2016-0007]
[11]
Soliman, M.I.; Taha, H.A.; Banjar, S.A. Intestinal parasitic infections among expatriate workers in Al-madina Al-munawarah; kingdom of Saudi Arabia, 2013.
[12]
VAN Dorssen, C.F.; Gordon, C.A.; Li, Y.; Williams, G.M.; Wang, Y.; Luo, Z.; Gobert, G.N.; You, H.; McManus, D.P.; Gray, D.J. Rodents, goats and dogs - their potential roles in the transmission of schistosomiasis in China. Parasitology, 2017, 144(12), 1633-1642.
[http://dx.doi.org/10.1017/S0031182017000907] [PMID: 28637527]
[13]
Li, H.; Dong, G-D.; Liu, J-M.; Gao, J-X.; Shi, Y-J.; Zhang, Y-G.; Jin, Y-M.; Lu, K.; Cheng, G.F.; Lin, J-J. Elimination of schistosomiasis japonica from formerly endemic areas in mountainous regions of southern China using a praziquantel regimen. Vet. Parasitol., 2015, 208(3-4), 254-258.
[http://dx.doi.org/10.1016/j.vetpar.2014.12.031] [PMID: 25591407]
[14]
Subhani, F.; Nizamuddin, R.; Qasim, A.; Idrees, N.; Ahmed, I.; Nizami, S.; Shakoor, S.; Beg, M.A. The emerging threat of schistosomiasis spread in Pakistan. Trop. Biomed., 2014, 31(1), 118-121.
[PMID: 24862051]
[15]
Alavi, S.M.; Salmanzadeh, S. 2016Schistosomiasis in Iran, from the past till elimination. Int. J. Infect., , 3.
[http://dx.doi.org/10.17795/iji-36075]
[16]
Wiwanitkit, V. Overview of clinical reports on urinary schistosomiasis in the tropical Asia. Pak. J. Med. Sci., 2005, 21, 499.
[17]
World Health Organization (WHO) report about the Schistosomiasis situation in Yemen. 2015.
[18]
Zhu, H.; Cai, S-X.; Liu, J-B.; Tu, Z-W.; Xia, J.; Shan, X-W.; Qiu, J.; Jiang, Y.; Xiao, Y.; Tang, L.; Huang, X.B. A spatial analysis of human Schistosoma japonicum infections in Hubei, China, during 2009-2014. Parasit. Vectors, 2016, 9(1), 529.
[http://dx.doi.org/10.1186/s13071-016-1817-6] [PMID: 27716421]
[19]
Latif, B.; Heo, C.C.; Razuin, R.; Shamalaa, D.V. Autochthonous human schistosomiasis; Malaysia, 2016.
[20]
Gordon, C.A.; Acosta, L.P.; Gray, D.J.; Olveda, R.M.; Jarilla, B.; Gobert, G.N.; Ross, A.G.; McManus, D.P. High prevalence of Schistosoma japonicum infection in Carabao from Samar Province, the Philippines: implications for transmission and control. PLoS Negl. Trop. Dis., 2012, 6(9) e1778
[http://dx.doi.org/10.1371/journal.pntd.0001778] [PMID: 23029571]
[21]
Liu, Y.; Zhong, B.; Wu, Z-S.; Liang, S.; Qiu, D-C.; Ma, X. Interruption of schistosomiasis transmission in mountainous and hilly regions with an integrated strategy: a longitudinal case study in Sichuan, China. Infect. Dis. Poverty, 2017, 6(1), 79.
[http://dx.doi.org/10.1186/s40249-017-0290-6] [PMID: 28385163]
[22]
Kalinda, C.; Chimbari, M.; Mukaratirwa, S. Implications of changing temperatures on the growth, fecundity and survival of intermediate host snails of schistosomiasis: a systematic review. Int. J. Environ. Res. Public Health, 2017, 14(1), 80.
[http://dx.doi.org/10.3390/ijerph14010080] [PMID: 28098789]
[23]
Mas-Coma, S.; Valero, M.A.; Bargues, M.D. Climate change effects on trematodiases, with emphasis on zoonotic fascioliasis and schistosomiasis. Vet. Parasitol., 2009, 163(4), 264-280.
[http://dx.doi.org/10.1016/j.vetpar.2009.03.024] [PMID: 19375233]
[24]
Jones, M.F.; Brady, F.J. Effects of water treatment processes on schistosome cercariae. Bull Natl Inst Health, 1947, 2(189), 109-130.
[PMID: 18921466]
[25]
Boulanger, D.; Schneider, D.; Sidikou, F.; Capron, A.; Chippaux, J-P.; Sellin, B. The oral route as a potential way of transmission of Schistosoma bovis in goats. J. Parasitol., 1999, 85(3), 464-467.
[http://dx.doi.org/10.2307/3285779] [PMID: 10386438]
[26]
Sow, S.; Polman, K.; Vereecken, K.; Vercruysse, J.; Gryseels, B.; de Vlas, S.J. The role of hygienic bathing after defecation in the transmission of Schistosoma mansoni. Trans. R. Soc. Trop. Med. Hyg., 2008, 102(6), 542-547.
[http://dx.doi.org/10.1016/j.trstmh.2008.02.016] [PMID: 18423504]
[27]
Kawata, K.; Krusé, C.W. The effect of sewage stabilization ponds on the eggs and miracidia of Schistosoma mansoni. Am. J. Trop. Med. Hyg., 1966, 15(6), 896-901.
[http://dx.doi.org/10.4269/ajtmh.1966.15.896] [PMID: 5959102]
[28]
Chandiwana, S.K. How Schistosoma mansoni eggs reach natural waterbodies. Trans. R. Soc. Trop. Med. Hyg., 1986, 80(6), 963-964.
[http://dx.doi.org/10.1016/0035-9203(86)90273-7] [PMID: 3111031]
[29]
Mostafa, O.M.; Bin Dajem, S.M.; Al-Qahtani, A.; Ibrahim, E.H.; Al-Quraishy, S.A. Developing species-specific primers to identify Bulinus truncatus and Bulinus beccari, the intermediate hosts of Schistosoma haematobium in Saudi Arabia. Gene, 2012, 499(2), 256-261.
[http://dx.doi.org/10.1016/j.gene.2012.03.024] [PMID: 22441124]
[30]
Shalaby, I.; Gherbawy, Y.; Banaja, A. Genetic diversity among Schistosoma mansoni population in the western region of Saudi Arabia. Trop. Biomed., 2011, 28(1), 90-101.
[PMID: 21602774]
[31]
Shati, A.A. Factors affecting the prevalence of human schistosomiasis in Aseer region, Saudi Arabia. J. Biol. Sci., 2009, 9, 815-819.
[http://dx.doi.org/10.3923/jbs.2009.815.819]
[32]
Hotez, P.J.; Savioli, L.; Fenwick, A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. PLoS Negl. Trop. Dis., 2012, 6(2) e1475
[http://dx.doi.org/10.1371/journal.pntd.0001475] [PMID: 22389729]
[33]
Steinmann, P.; Keiser, J.; Bos, R.; Tanner, M.; Utzinger, J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect. Dis., 2006, 6(7), 411-425.
[http://dx.doi.org/10.1016/S1473-3099(06)70521-7] [PMID: 16790382]
[34]
Davis, G.; Wilke, T.; Zhang, Y.; Xu, X-J.; Qiu, C-P.; Spolsky, C.; Qiu, D-C.; Li, Y.; Xia, M-Y.; Feng, Z. Snail-Schistosoma, Paragonimus interactions in China: population ecology, genetic diversity, coevolution and emerging diseases. Malacologia, 1999, 41, 355-377.
[35]
Afshan, K.; Beg, M.A.; Ahmad, I.; Ahmad, M.M.; Qayyum, M. Freshwater snail fauna of Pothwar region, Pakistan. Pak. J. Zool., 2013, 45, 227-233.
[36]
Arshad, G.M.; Maqbool, A.; Qamar, M.F.; Bukhari, S.M.H.; Hashmi, H.A.; Ashraf, M. Prevalence and ecology of fresh water snails in some selected districts of southern Punjab, Pakistan. Pak. J. Life Soc. Sci., 2011, 9, 17-20.
[37]
Sankarappan, A.; Chellapandian, B.; Vimalanathan, A.P.; Mani, K.; Sundaram, D.; Muthukalingan, K. Vector ecology of human schistosomiasis in south India and description of a new species of the genus Ferrissia (Mollusca: Gastropoda: Planorbidae). J. Vector Borne Dis., 2015, 52(3), 201-207.
[PMID: 26418649]
[38]
Devkota, R.; Brant, S.V.; Loker, E.S. The Schistosoma indicum species group in Nepal: presence of a new lineage of schistosome and use of the Indoplanorbis exustus species complex of snail hosts. Int. J. Parasitol., 2015, 45(13), 857-870.
[http://dx.doi.org/10.1016/j.ijpara.2015.07.008] [PMID: 26385438]
[39]
Islam, M.; Begum, N.; Alam, M.; Mamun, M. Epidemiology of intestinal schistosomiasis in ruminants of Bangladesh. Journal of the Bangladesh Agricultural University, 2012, 9, 221-228.
[http://dx.doi.org/10.3329/jbau.v9i2.10990]
[40]
Balahbib, A.; Amarir, F.; Corstjens, P.L.; de Dood, C.J.; van Dam, G.J.; Hajli, A.; Belhaddad, M.; El Mansouri, B.; Sadak, A.; Rhajaoui, M.; Adlaoui, E.B. Selecting accurate post-elimination monitoring tools to prevent reemergence of urogenital schistosomiasis in Morocco: a pilot study. Infect. Dis. Poverty, 2017, 6(1), 75.
[http://dx.doi.org/10.1186/s40249-017-0289-z] [PMID: 28381240]
[41]
Colley, D.G.; Andros, T.S.; Campbell, C.H., Jr Schistosomiasis is more prevalent than previously thought: what does it mean for public health goals, policies, strategies, guidelines and intervention programs? Infect. Dis. Poverty, 2017, 6(1), 63.
[http://dx.doi.org/10.1186/s40249-017-0275-5] [PMID: 28327187]
[42]
Zhou, X-N.; Guo, J-G.; Wu, X-H.; Jiang, Q-W.; Zheng, J.; Dang, H.; Wang, X-H.; Xu, J.; Zhu, H-Q.; Wu, G-L.; Li, Y.S.; Xu, X.J.; Chen, H.G.; Wang, T.P.; Zhu, Y.C.; Qiu, D.C.; Dong, X.Q.; Zhao, G.M.; Zhang, S.J.; Zhao, N.Q.; Xia, G.; Wang, L.Y.; Zhang, S.Q.; Lin, D.D.; Chen, M.G.; Hao, Y. Epidemiology of schistosomiasis in the People’s Republic of China, 2004. Emerg. Infect. Dis., 2007, 13(10), 1470-1476.
[http://dx.doi.org/10.3201/eid1310.061423] [PMID: 18257989]
[43]
Ross, A.G.; Sleigh, A.C.; Li, Y.; Davis, G.M.; Williams, G.M.; Jiang, Z.; Feng, Z.; McManus, D.P. Schistosomiasis in the People’s Republic of China: prospects and challenges for the 21st century. Clin. Microbiol. Rev., 2001, 14(2), 270-295.
[http://dx.doi.org/10.1128/CMR.14.2.270-295.2001] [PMID: 11292639]
[44]
McManus, D.P.; Gray, D.J.; Li, Y.; Feng, Z.; Williams, G.M.; Stewart, D.; Rey-Ladino, J.; Ross, A.G. Schistosomiasis in the People’s Republic of China: the era of the Three Gorges Dam. Clin. Microbiol. Rev., 2010, 23(2), 442-466.
[http://dx.doi.org/10.1128/CMR.00044-09] [PMID: 20375361]
[45]
Xu, R.; Feng, J.; Hong, Y.; Lv, C.; Zhao, D.; Lin, J.; Lu, K.; Li, H.; Liu, J.; Cao, X.; Wang, T.; Zai, J.; Wang, Z.; Jia, B.; Han, Q.; Zhu, C. A novel colloidal gold immunochromatography assay strip for the diagnosis of schistosomiasis japonica in domestic animals. Infect. Dis. Poverty, 2017, 6(1), 84.
[http://dx.doi.org/10.1186/s40249-017-0297-z] [PMID: 28388965]
[46]
Olveda, R.M.; Acosta, L.P.; Tallo, V.; Baltazar, P.I.; Lesiguez, J.L.S.; Estanislao, G.G.; Ayaso, E.B.; Monterde, D.B.S.; Ida, A.; Watson, N.; McDonald, E.A.; Wu, H.W.; Kurtis, J.D.; Friedman, J.F. Efficacy and safety of praziquantel for the treatment of human schistosomiasis during pregnancy: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Infect. Dis., 2016, 16(2), 199-208.
[http://dx.doi.org/10.1016/S1473-3099(15)00345-X] [PMID: 26511959]
[47]
Rujeni, N.; Morona, D.; Ruberanziza, E.; Mazigo, H.D. Schistosomiasis and soil-transmitted helminthiasis in Rwanda: an update on their epidemiology and control. Infect. Dis. Poverty, 2017, 6(1), 8.
[http://dx.doi.org/10.1186/s40249-016-0212-z] [PMID: 28245883]
[48]
Savioli, L.; Albonico, M.; Colley, D.G.; Correa-Oliveira, R.; Fenwick, A.; Green, W.; Kabatereine, N.; Kabore, A.; Katz, N.; Klohe, K.; LoVerde, P.T.; Rollinson, D.; Stothard, J.R.; Tchuem Tchuenté, L.A.; Waltz, J.; Zhou, X.N. Building a global schistosomiasis alliance: an opportunity to join forces to fight inequality and rural poverty. Infect. Dis. Poverty, 2017, 6(1), 65.
[http://dx.doi.org/10.1186/s40249-017-0280-8] [PMID: 28330495]
[49]
Bergquist, R.; Utzinger, J.; Keiser, J. Controlling schistosomiasis with praziquantel: How much longer without a viable alternative? Infect. Dis. Poverty, 2017, 6(1), 74.
[http://dx.doi.org/10.1186/s40249-017-0286-2] [PMID: 28351414]
[50]
Kabuyaya, M.; Chimbari, M.J.; Manyangadze, T.; Mukaratirwa, S. Efficacy of praziquantel on Schistosoma haematobium and re-infection rates among school-going children in the Ndumo area of uMkhanyakude district, KwaZulu-Natal, South Africa. Infect. Dis. Poverty, 2017, 6(1), 83.
[http://dx.doi.org/10.1186/s40249-017-0293-3] [PMID: 28385154]
[51]
Ohmae, H.; Iwanaga, Y.; Nara, T.; Matsuda, H.; Yasuraoka, K. Biological characteristics and control of intermediate snail host of Schistosoma japonicum. Parasitol. Int., 2003, 52(4), 409-417.
[http://dx.doi.org/10.1016/S1383-5769(03)00058-8] [PMID: 14665400]
[52]
Wang, F.; Ma, Y.; Sun, L.; Hong, Q.; Gao, Y.; Zhang, C.; Du, G.; Lu, D.; Sun, Z.; Wang, W. 2016, Integration and demonstration of key techniques in surveillance and forecast of schistosomiasis in Jiangsu Province III Development of a machine simultaneously integrating mechanized environmental cleaning and automatic mollusciciding. Zhongguo xue xi chong bing fang zhi za zhi= Chinese journal of schistosomiasis control, 28, 5-10.
[53]
Dai, J-R.; Li, Y-Z.; Wang, W.; Xing, Y-T.; Qu, G-L.; Liang, Y-S. Resistance to niclosamide in Oncomelania hupensis, the intermediate host of Schistosoma japonicum: should we be worried? Parasitology, 2015, 142(2), 332-340.
[http://dx.doi.org/10.1017/S0031182014000870] [PMID: 25003984]
[54]
Gu, X.G. Main problems in application of niclosamide in field. Chin. J. Schisto. Control., 2004, 16, 159. (in Chinese).
[55]
Lu, D.B. Some problems in application of niclosamide. Chin. J. Schisto. Control., 2004, 16, 159-160. (in Chinese).
[56]
Zhu, H.; Zhong, B.; Zhang, G.; Tang, S.; Cao, C.; Zhang, X.; Jia, B.; Zhang, Y.; Li, J.; Fu, T. Molluscicidal effect of film on ditches in mountainous schistosomiasis endemic regions. Zhongguo xue xi chong bing fang zhi za zhi= Chinese journal of schistosomiasis control, 2011, 23, 128-132.
[57]
Liu, H.; Zhong, C.; Wan, G.; Cheng, B.; Wang, Y.; Tian, R.; Cheng, A.; Xia, Z.; Yang, S.; Ding, Z. Molluscicidal effect of plastic film mulch covering method. Zhongguo xue xi chong bing fang zhi za zhi. Chinese J. Schisto. Cont., 2013, 25, 399-401.
[58]
Zheng, S.; Zhou, Y.; Li, L.; Wu, J.; Yao, B.; Zhu, S.; Wei, C.; Li, F.; Hu, B.; Ren, G. Short-term effect of black film covering on Oncomelania hupensis snail control in marshland and lake regions. Zhongguo xue xi chong bing fang zhi za zhi= Chinese journal of schistosomiasis control., 2013, 25, 357-361.
[59]
Martins, M.H.; Fracarolli, L.; Vieira, T.M.; Dias, H.J.; Cruz, M.G.; Deus, C.C.; Nicolella, H.D.; Stefani, R.; Rodrigues, V.; Tavares, D.C.; Magalhães, L.G.; Crotti, A.E. Schistosomicidal Effects of the Essential Oils of Citrus limonia and Citrus reticulata Against Schistosoma mansoni. Chem. Biodivers., 2017, 14(1), 14.
[http://dx.doi.org/10.1002/cbdv.201600194] [PMID: 27936310]
[60]
Doenhoff, M.J.; Cioli, D.; Utzinger, J. Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr. Opin. Infect. Dis., 2008, 21(6), 659-667.
[http://dx.doi.org/10.1097/QCO.0b013e328318978f] [PMID: 18978535]
[61]
Fallon, P.G.; Doenhoff, M.J. Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. Am. J. Trop. Med. Hyg., 1994, 51(1), 83-88.
[http://dx.doi.org/10.4269/ajtmh.1994.51.83] [PMID: 8059919]
[62]
Botros, S.S.; Bennett, J.L. Praziquantel resistance. Expert Opin. Drug Discov., 2007, 2(s1), S35-S40.
[http://dx.doi.org/10.1517/17460441.2.S1.S35] [PMID: 23489031]
[63]
Mathers, C.D.; Ezzati, M.; Lopez, A.D. Measuring the burden of neglected tropical diseases: the global burden of disease framework. PLoS Negl. Trop. Dis., 2007, 1(2) e114
[http://dx.doi.org/10.1371/journal.pntd.0000114] [PMID: 18060077]
[64]
King, C.H. Parasites and poverty: the case of schistosomiasis. Acta Trop., 2010, 113(2), 95-104.
[http://dx.doi.org/10.1016/j.actatropica.2009.11.012] [PMID: 19962954]
[65]
Mduluza, T.; Mutapi, F. Putting the treatment of paediatric schistosomiasis into context. Infect. Dis. Poverty, 2017, 6(1), 85.
[http://dx.doi.org/10.1186/s40249-017-0300-8] [PMID: 28388940]
[66]
Stothard, J.R.; Campbell, S.J.; Osei-Atweneboana, M.Y.; Durant, T.; Stanton, M.C.; Biritwum, N-K.; Rollinson, D.; Ombede, D.R.E.; Tchuem-Tchuenté, L-A. Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support ‘end game’ interventions. Infect. Dis. Poverty, 2017, 6(1), 10.
[http://dx.doi.org/10.1186/s40249-016-0215-9] [PMID: 28088239]
[67]
Sun, L-P.; Wang, W.; Zuo, Y-P.; Hong, Q-B.; Du, G-L.; Ma, Y-C.; Wang, J.; Yang, G-J.; Zhu, D-J.; Liang, Y-S. A multidisciplinary, integrated approach for the elimination of schistosomiasis: a longitudinal study in a historically hyper-endemic region in the lower reaches of the Yangtze River, China from 2005 to 2014. Infect. Dis. Poverty, 2017b, 6(1), 56.
[http://dx.doi.org/10.1186/s40249-017-0270-x] [PMID: 28288689]
[68]
Sun, L-P.; Wang, W.; Hong, Q-B.; Li, S-Z.; Liang, Y-S.; Yang, H-T.; Zhou, X-N. Approaches being used in the national schistosomiasis elimination programme in China: a review. Infect. Dis. Poverty, 2017a, 6(1), 55.
[http://dx.doi.org/10.1186/s40249-017-0271-9] [PMID: 28292327]
[69]
Tchuem Tchuenté, L.A.; Rollinson, D.; Stothard, J.R.; Molyneux, D. Moving from control to elimination of schistosomiasis in sub-Saharan Africa: time to change and adapt strategies. Infect. Dis. Poverty, 2017, 6(1), 42.
[http://dx.doi.org/10.1186/s40249-017-0256-8] [PMID: 28219412]
[70]
Li, H.; Wang, W. Apropos: critical analysis of molluscicide application in schistosomiasis control programs in Brazil. Infect. Dis. Poverty, 2017, 6(1), 54.
[http://dx.doi.org/10.1186/s40249-017-0246-x] [PMID: 28270227]
[71]
Gray, D.J.; Williams, G.M.; Li, Y.; McManus, D.P. Transmission dynamics of Schistosoma japonicum in the lakes and marshlands of China. PLoS One, 2008, 3(12) e4058
[http://dx.doi.org/10.1371/journal.pone.0004058] [PMID: 19115007]
[72]
Li-Juan, Z.; Zhi-Min, X.; Ying-Jun, Q.; Hui, D.; Shan, L.; Jing, X.; Shi-Zhu, L.; Xiao-Nong, Z. Endemic status of schistosomiasis in People’s Republic of China in 2015. Zhongguo xue xi chong bing fang zhi za zhi. Chinese J. Schisto. Cont., 2016, 28, 611-617.
[73]
Sagin, D.; Ismail, G.; Fui, J.; Jok, J. Schistosomiasis malayensislike infection among the Penan and other interior tribes (Orang Ulu) in upper Rejang River Basin Sarawak Malaysia. 2001.
[74]
Farahnak, A.; Essalat, M. A study on cercarial dermatitis in Khuzestan province, south western Iran. BMC Public Health, 2003, 3, 35.
[http://dx.doi.org/10.1186/1471-2458-3-35] [PMID: 14604437]
[75]
Iqbal, Z.; Lateef, M.; Akhtar, M.S.; Ghayur, M.N.; Gilani, A.H. In vivo anthelmintic activity of ginger against gastrointestinal nematodes of sheep. J. Ethnopharmacol., 2006, 106(2), 285-287.
[http://dx.doi.org/10.1016/j.jep.2005.12.031] [PMID: 16443342]
[76]
Anvikar, A. Cercarien Hullen Reaction for the assessment of human schistosomiasis in India. Parasit. Dis., 2006, 30, 181-183.
[77]
Gholamreza, M.; Jafar, M.; Allahbedasht, M.; Nikkhooy, A.; Mahammad, K.; Rokni, M. Survey of urinary schistosomiasis in Iran. Pak. Med. J. Sci., 2008, 24, 857-860.
[78]
Raso, G.; Li, Y.; Zhao, Z.; Balen, J.; Williams, G.M.; McManus, D.P. Spatial distribution of human Schistosoma japonicum infections in the Dongting Lake Region, China. PLoS One, 2009, 4(9) e6947
[http://dx.doi.org/10.1371/journal.pone.0006947] [PMID: 19759819]
[79]
Ahmed, B.A. Two Practical and Cost Effective Methods for Urinary Schistosomiasis Screening in Yemeni Schoolchildren. Iran. J. Public Health, 2009, 38.
[80]
Niaz, S.; Tanveer, A.; Qureshi, A. Prevalence of humans schistosomiasis in different areas of Punjab Pakistan. Pak. J. Sci., 2010, 62, 160-162.
[81]
Zhou, Y-B.; Liang, S.; Chen, G-X.; Rea, C.; He, Z-G.; Zhang, Z-J.; Wei, J-G.; Zhao, G-M.; Jiang, Q-W. An integrated strategy for transmission control of Schistosoma japonicum in a marshland area of China: findings from a five-year longitudinal survey and mathematical modeling. Am. J. Trop. Med. Hyg., 2011, 85(1), 83-88.
[http://dx.doi.org/10.4269/ajtmh.2011.10-0574] [PMID: 21734130]
[82]
Al-Shamiri, A.H.; Al-Taj, M.A.; Ahmed, A.S. Prevalence and co-infections of schistosomiasis/hepatitis B and C viruses among school children in an endemic areas in Taiz, Yemen. Asian Pac. J. Trop. Med., 2011, 4(5), 404-408.
[http://dx.doi.org/10.1016/S1995-7645(11)60113-2] [PMID: 21771686]
[83]
Mahdavi, S.A.; Farahnak, A.; Mousavi, S.J.; Mobedi, I.; Rezaeian, M.; Golmohamadi, T.; Azadeh, H.; Gohardehi, S. Prevalence of schistosome induced cercarial dermatitis in north of Iran. Asian Pac. J. Trop. Dis., 2013, 3, 37-40.
[http://dx.doi.org/10.1016/S2222-1808(13)60008-0]
[84]
Taha, H.A.; Soliman, M.I.; Banjar, S.A.N. Intestinal parasitic infections among expatriate workers in Al-Madina Al-Munawarah, Kingdom of Saudi Arabia. Trop. Biomed., 2013, 30(1), 78-88.
[PMID: 23665711]
[85]
Sady, H.; Al-Mekhlafi, H.M.; Mahdy, M.A.; Lim, Y.A.; Mahmud, R.; Surin, J. Prevalence and associated factors of Schistosomiasis among children in Yemen: implications for an effective control programme. PLoS Negl. Trop. Dis., 2013, 7(8) e2377
[http://dx.doi.org/10.1371/journal.pntd.0002377] [PMID: 23991235]
[86]
Bassiouny, H.K.; Hasab, A.A.; El-Nimr, N.A.; Al-Shibani, L.A.; Al-Waleedi, A.A. Rapid diagnosis of schistosomiasis in Yemen using a simple questionnaire and urine reagent strips. East. Mediterr. Health J., 2014, 20(4), 242-249.
[http://dx.doi.org/10.26719/2014.20.4.242] [PMID: 24952121]
[87]
Sady, H.; Al-Mekhlafi, H.M.; Atroosh, W.M.; Al-Delaimy, A.K.; Nasr, N.A.; Dawaki, S.; Al-Areeqi, M.A.; Ithoi, I.; Abdulsalam, A.M.; Chua, K.H.; Surin, J. Knowledge, attitude, and practices towards schistosomiasis among rural population in Yemen. Parasit. Vectors, 2015, 8, 436.
[http://dx.doi.org/10.1186/s13071-015-1050-8] [PMID: 26302747]
[88]
Khademvatan, S.; Salmanzadeh, S.; Foroutan-Rad, M.; Ghomeshi, M. Elimination of urogenital schistosomiasis in Iran: past history and the current situation. Parasitology, 2016, 143(11), 1390-1396.
[http://dx.doi.org/10.1017/S0031182016000883] [PMID: 27279000]
[89]
Zhang, L.J.; Xu, Z.M.; Qian, Y.J.; Dang, H.; Lu, S.; Xu, J.; Li, S.Z.; Zhou, X.N. Endemic situation of schistosomiasis in People’s Republic of China. Chin J Schisto Control., 2016, 28, 611-617.
[90]
Tekwu, E.M.; Bosompem, K.M.; Anyan, W.K.; Appiah-Opong, R.; Owusu, K.B-A.; Tettey, M.D.; Kissi, F.A.; Appiah, A.A.; Penlap Beng, V.; Nyarko, A.K. In Vitro Assessment of Anthelmintic Activities of Rauwolfia vomitoria (Apocynaceae) Stem Bark and Roots against Parasitic Stages of Schistosoma mansoni and Cytotoxic Study. In: J Parasitol. Res; , 2017.
[91]
Rocha, J.A.; Andrade, I.M.; Véras, L.M.; Quelemes, P.V.; Lima, D.F.; Soares, M.J.; Pinto, P.L.; Mayo, S.J.; Ivanova, G.; Rangel, M.; Correia, M.; Mafud, A.C.; Mascarenhas, Y.P.; Delerue-Matos, C.; de Moraes, J.; Eaton, P.; Leite, J.R. Anthelmintic, Antibacterial and Cytotoxicity Activity of Imidazole Alkaloids from Pilocarpus microphyllus Leaves. Phytother. Res., 2017, 31(4), 624-630.
[http://dx.doi.org/10.1002/ptr.5771] [PMID: 28111828]
[92]
Sanderson, L.; Bartlett, A.; Whitfield, P.J. In vitro and in vivo studies on the bioactivity of a ginger (Zingiber officinale) extract towards adult schistosomes and their egg production. J. Helminthol., 2002, 76(3), 241-247.
[http://dx.doi.org/10.1079/JOH2002116] [PMID: 12363378]
[93]
Wangchuk, P.; Giacomin, P.R.; Pearson, M.S.; Smout, M.J.; Loukas, A. Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms. Sci. Rep., 2016, 6, 32101.
[http://dx.doi.org/10.1038/srep32101] [PMID: 27572696]
[94]
Yones, D.A.; Badary, D.M.; Sayed, H.M.; Bayoumi, S.A.; Khalifa, A.A.; El-Moghazy, A.M. Comparative Evaluation of Anthelmintic Activity of Edible and Ornamental Pomegranate Ethanolic Extracts against Schistosoma mansoni. BioMed Res. Int., 2016, 2016, 2872708
[http://dx.doi.org/10.1155/2016/2872708] [PMID: 27990425]
[95]
Quelemes, P.V.; Perfeito, M.L.; Guimarães, M.A.; dos Santos, R.C.; Lima, D.F.; Nascimento, C.; Silva, M.P.; Soares, M.J.S.; Ropke, C.D.; Eaton, P.; de Moraes, J.; Leite, J.R. Effect of neem (Azadirachta indica A. Juss) leaf extract on resistant Staphylococcus aureus biofilm formation and Schistosoma mansoni worms. J. Ethnopharmacol., 2015, 175, 287-294.
[http://dx.doi.org/10.1016/j.jep.2015.09.026] [PMID: 26408045]
[96]
de Castro, C.C.; Costa, P.S.; Laktin, G.T.; de Carvalho, P.H.; Geraldo, R.B.; de Moraes, J.; Pinto, P.L.; Couri, M.R.; Pinto, Pde.F.; Da Silva Filho, A.A. Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase. Phytomedicine, 2015, 22(10), 921-928.
[http://dx.doi.org/10.1016/j.phymed.2015.06.009] [PMID: 26321741]
[97]
Aleixo de Carvalho, L.S.; Geraldo, R.B.; de Moraes, J.; Silva Pinto, P.L.; de Faria Pinto, P.; Pereira, Odos.S., Jr; Da Silva Filho, A.A. Schistosomicidal activity and docking of Schistosoma mansoni ATPDase 1 with licoflavone B isolated from Glycyrrhiza inflata (Fabaceae). Exp. Parasitol., 2015, 159, 207-214.
[http://dx.doi.org/10.1016/j.exppara.2015.09.015] [PMID: 26454044]
[98]
Niaz, S.; Akhtar, T.; Shams, S. Treatment of bovine schistosomiasis with medicinal plant Veronia anthelmintica (Kaliziri), an alternative approach. Afr. J. Tradit. Complement. Altern. Med., 2015, 12, 78-83.
[http://dx.doi.org/10.4314/ajtcam.v12i6.6S]
[99]
de Oliveira, R.N.; Rehder, V.L.G.; Oliveira, A.S.S.; Jeraldo, Vde.L.; Linhares, A.X.; Allegretti, S.M. Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni. Exp. Parasitol., 2014, 139, 63-72.
[http://dx.doi.org/10.1016/j.exppara.2014.02.010] [PMID: 24602876]
[100]
Godinho, L.S.; Aleixo de Carvalho, L.S.; Barbosa de Castro, C.C.; Dias, M.M.; Pinto, Pde.F.; Crotti, A.E.; Pinto, P.L.; de Moraes, J.; Da Silva Filho, A.A. Anthelmintic activity of crude extract and essential oil of Tanacetum vulgare (Asteraceae) against adult worms of Schistosoma mansoni. ScientificWorldJournal, 2014, 2014, 460342
[http://dx.doi.org/10.1155/2014/460342] [PMID: 24672320]
[101]
Aguiar, G.P.; Melo, N.I.; Wakabayashi, K.A.; Lopes, M.H.; Mantovani, A.L.; Dias, H.J.; Fukui, M.J.; Keles, L.C.; Rodrigues, V.; Groppo, M.; Silva-Filho, A.A.; Cunha, W.R.; Magalhães, L.G.; Crotti, A.E. Chemical composition and in vitro schistosomicidal activity of the essential oil from the flowers of Bidens sulphurea (Asteraceae). Nat. Prod. Res., 2013, 27(10), 920-924.
[http://dx.doi.org/10.1080/14786419.2012.671314] [PMID: 22452598]
[102]
Veras, L.M.; Guimaraes, M.A.; Campelo, Y.D.; Vieira, M.M.; Nascimento, C.; Lima, D.F.; Vasconcelos, L.; Nakano, E.; Kuckelhaus, S.S.; Batista, M.C.; Leite, J.R.; Moraes, J. Activity of epiisopiloturine against Schistosoma mansoni. Curr. Med. Chem., 2012, 19(13), 2051-2058.
[http://dx.doi.org/10.2174/092986712800167347] [PMID: 22420337]
[103]
de Moraes, J.; Nascimento, C.; Yamaguchi, L.F.; Kato, M.J.; Nakano, E. Schistosoma mansoni: in vitro schistosomicidal activity and tegumental alterations induced by piplartine on schistosomula. Exp. Parasitol., 2012, 132(2), 222-227.
[http://dx.doi.org/10.1016/j.exppara.2012.07.004] [PMID: 22796749]
[104]
Ramalhete, C.; Magalhães, L.G.; Rodrigues, V.; Mulhovo, S.; Da Silva Filho, A.A.; Ferreira, M-J.U. In vitro schistosomicidal activity of balsaminol F and karavilagenin C. Planta Med., 2012, 78(18), 1912-1917.
[http://dx.doi.org/10.1055/s-0032-1327832] [PMID: 23096257]
[105]
Cunha, N.L.; Uchôa, C.J.M.; Cintra, L.S.; Souza, H.C.D.; Peixoto, J.A.; Silva, C.P.; Magalhães, L.G.; Gimenez, V.M.M.; Groppo, M.; Rodrigues, V. In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds; Evidence-Based Comp. Alternative Med, 2012.
[106]
de Melo, N.I.; Mantovani, A.L.; de Oliveira, P.F.; Groppo, M.; Filho, A.A.; Rodrigues, V.; Cunha, W.R.; Tavares, D.C.; Magalhaes, L.G.; Crottii, A.E. Antischistosomal and Cytotoxic Effects of the Essential Oil of Tetradenia riparia (Lamiaceae). Nat. Prod. Commun., 2015, 10(9), 1627-1630.
[http://dx.doi.org/10.1177/1934578X1501000934] [PMID: 26594774]
[107]
Kamel, E.G.; El-Emam, M.A.; Mahmoud, S.S.; Fouda, F.M.; Bayaumy, F.E. Parasitological and biochemical parameters in Schistosoma mansoni-infected mice treated with methanol extract from the plants Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban. Parasitol. Int., 2011, 60(4), 388-392.
[http://dx.doi.org/10.1016/j.parint.2011.06.016] [PMID: 21740980]
[108]
McGaw, L.J.; Rabe, T.; Sparg, S.G.; Jäger, A.K.; Eloff, J.N.; van Staden, J. An investigation on the biological activity of Combretum species. J. Ethnopharmacol., 2001, 75(1), 45-50.
[http://dx.doi.org/10.1016/S0378-8741(00)00405-0] [PMID: 11282442]
[109]
Tonuci, L.R.; Melo, N.I.d.; Dias, H.J.; Wakabayashi, K.A.; Aguiar, G.P.; Aguiar, D.P.; Mantovani, A.L.; Ramos, R.C.; Groppo, M.; Rodrigues, V. In vitro schistosomicidal effects of the essential oil of Tagetes erecta. Rev. Bras. Farmacogn., 2012, 22, 88-93.
[http://dx.doi.org/10.1590/S0102-695X2011005000202]
[110]
de Melo, N.I.; Magalhaes, L.G.; de Carvalho, C.E.; Wakabayashi, K.A.; de P Aguiar, G.; Ramos, R.C.; Mantovani, A.L.; Turatti, I.C.; Rodrigues, V.; Groppo, M.; Cunha, W.R.; Veneziani, R.C.; Crotti, A.E. Schistosomicidal activity of the essential oil of Ageratum conyzoides L. (Asteraceae) against adult Schistosoma mansoni worms. Molecules, 2011, 16(1), 762-773.
[http://dx.doi.org/10.3390/molecules16010762] [PMID: 21245809]
[111]
Caixeta, S.C.; Magalhães, L.G.; de Melo, N.I.; Wakabayashi, K.A.; Aguiar, Gde.P.; Aguiar, Dde.P.; Mantovani, A.L.; Alves, J.M.; Oliveira, P.F.; Tavares, D.C.; Groppo, M.; Rodrigues, V.; Cunha, W.R.; Veneziani, R.C.; da Silva Filho, A.A.; Crotti, A.E. Chemical composition and in vitro schistosomicidal activity of the essential oil of Plectranthus neochilus grown in Southeast Brazil. Chem. Biodivers., 2011, 8(11), 2149-2157.
[http://dx.doi.org/10.1002/cbdv.201100167] [PMID: 22083928]
[112]
Parreira, N.A.; Magalhães, L.G.; Morais, D.R.; Caixeta, S.C.; de Sousa, J.P.; Bastos, J.K.; Cunha, W.R.; Silva, M.L.; Nanayakkara, N.P.; Rodrigues, V.; da Silva Filho, A.A. Antiprotozoal, schistosomicidal, and antimicrobial activities of the essential oil from the leaves of Baccharis dracunculifolia. Chem. Biodivers., 2010, 7(4), 993-1001.
[http://dx.doi.org/10.1002/cbdv.200900292] [PMID: 20397234]
[113]
Braguine, C.G.; Costa, E.S.; Magalhaes, L.G.; Rodrigues, V.; da Silva Filho, A.A.; Bastos, J.K.; Silva, M.L.; Cunha, W.R.; Januario, A.H.; Pauletti, P.M. Schistosomicidal evaluation of Zanthoxylum naranjillo and its isolated compounds against Schistosoma mansoni adult worms. Zeitschrift für Naturforschung C., 2009, 64, 793-797.
[http://dx.doi.org/10.1515/znc-2009-11-1207]
[114]
Magalhães, L.G.; Kapadia, G.J.; da Silva Tonuci, L.R.; Caixeta, S.C.; Parreira, N.A.; Rodrigues, V.; Da Silva Filho, A.A. In vitro schistosomicidal effects of some phloroglucinol derivatives from Dryopteris species against Schistosoma mansoni adult worms. Parasitol. Res., 2010, 106(2), 395-401.
[http://dx.doi.org/10.1007/s00436-009-1674-8] [PMID: 19898869]
[115]
Magalhães, L.G.; Machado, C.B.; Morais, E.R.; Moreira, E.B.; Soares, C.S.; da Silva, S.H.; Da Silva Filho, A.A.; Rodrigues, V. In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms. Parasitol. Res., 2009, 104(5), 1197-1201.
[http://dx.doi.org/10.1007/s00436-008-1311-y] [PMID: 19096877]
[116]
Bah, S.; Diallo, D.; Dembélé, S.; Paulsen, B.S. Ethnopharmacological survey of plants used for the treatment of schistosomiasis in Niono District, Mali. J. Ethnopharmacol., 2006, 105(3), 387-399.
[http://dx.doi.org/10.1016/j.jep.2005.11.026] [PMID: 16414223]
[117]
Mohamed, A.M.; Metwally, N.M.; Mahmoud, S.S. Sativa seeds against Schistosoma mansoni different stages. Mem. Inst. Oswaldo Cruz, 2005, 100(2), 205-211.
[http://dx.doi.org/10.1590/S0074-02762005000200016] [PMID: 16021310]
[118]
Alawa, C.B.; Adamu, A.M.; Gefu, J.O.; Ajanusi, O.J.; Abdu, P.A.; Chiezey, N.P.; Alawa, J.N.; Bowman, D.D. In vitro screening of two Nigerian medicinal plants (Vernonia amygdalina and Annona senegalensis) for anthelmintic activity. Vet. Parasitol., 2003, 113(1), 73-81.
[http://dx.doi.org/10.1016/S0304-4017(03)00040-2] [PMID: 12651218]
[119]
Mølgaard, P.; Nielsen, S.B.; Rasmussen, D.E.; Drummond, R.B.; Makaza, N.; Andreassen, J. Anthelmintic screening of Zimbabwean plants traditionally used against schistosomiasis. J. Ethnopharmacol., 2001, 74(3), 257-264.
[http://dx.doi.org/10.1016/S0378-8741(00)00377-9] [PMID: 11274827]
[120]
Sparg, S.G.; van Staden, J.; Jäger, A.K. Efficiency of traditionally used South African plants against schistosomiasis. J. Ethnopharmacol., 2000, 73(1-2), 209-214.
[http://dx.doi.org/10.1016/S0378-8741(00)00310-X] [PMID: 11025158]
[121]
Colley, D.G.; Loker, E.S. New Tools for Old Questions: How Strictly Human Are “Human Schistosomes”-And Does It Matter? J. Infect. Dis., 2018, 218(3), 344-346.
[http://dx.doi.org/10.1093/infdis/jiy030] [PMID: 29365121]
[122]
Sokolow, S.H.; Wood, C.L.; Jones, I.J.; Lafferty, K.D.; Kuris, A.M.; Hsieh, M.H.; De Leo, G.A. To reduce the global burden of human schistosomiasis use ‘old fashioned’ snail control. Trends Parasitol., 2018, 34(1), 23-40.
[http://dx.doi.org/10.1016/j.pt.2017.10.002] [PMID: 29126819]
[123]
Ondigo, B.N.; Ndombi, E.M.; Nicholson, S.C.; Oguso, J.K.; Carter, J.M.; Kittur, N.; Secor, W.E.; Karanja, D.M.S.; Colley, D.G. Functional studies of T-regulatory lymphocytes in human schistosomiasis in Western Kenya. Am. J. Trop. Med. Hyg., 2018, 98(6), 1770-1781.
[http://dx.doi.org/10.4269/ajtmh.17-0966] [PMID: 29692308]
[124]
Kamdem, S.D.; Moyou-Somo, R.; Brombacher, F.; Nono, J.K. Host regulators of Liver fibrosis during Human Schistosomiasis. Front. Immunol., 2018, 9, 2781.
[http://dx.doi.org/10.3389/fimmu.2018.02781] [PMID: 30546364]
[125]
Bergquist, R.; Elmorshedy, H. Artemether and praziquantel: origin, mode of action, impact, and suggested application for effective control of human schistosomiasis. Tropical medicine and infectious disease., 2018, 3(4), 125.
[http://dx.doi.org/ 10.3390/tropicalmed3040125]
[126]
Halstead, N.T.; Hoover, C.M.; Arakala, A.; Civitello, D.J.; De Leo, G.A.; Gambhir, M.; Johnson, S.A.; Jouanard, N.; Loerns, K.A.; McMahon, T.A.; Ndione, R.A.; Nguyen, K.; Raffel, T.R.; Remais, J.V.; Riveau, G.; Sokolow, S.H.; Rohr, J.R. Agrochemicals increase risk of human schistosomiasis by supporting higher densities of intermediate hosts. Nat. Commun., 2018, 9(1), 837.
[http://dx.doi.org/10.1038/s41467-018-03189-w] [PMID: 29483531]


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VOLUME: 20
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Year: 2020
Published on: 23 July, 2020
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