Introduction: Capsella bursa-pastoris(L.) Medic is a traditional herb of the genus
Capsella with long-standing Pakistan, India, Iraq, Cyprus, Turkey, Iran, Azarbayjan, Europe, Saudi
Arabia, China and many other regions of Asian countries ethnomedical records. Preliminary studies
from the animal model have provided valuable scientific evidence for its use, also the novel bioactive
Aim: This review aims to summarize the ethnopharmacology, selected scientific evidence on the
pharmacological properties and phytochemistry of C. bursa-pastoris(L.) Medic over the past 38 years
while identifying potential areas of further development of this herb as an economical adjunct.
Methods: The review covers literature pertaining to the evidence-based on ethnopharmacology,
therapeutic potential, and phytochemistry of C. bursa-pastoris(L.) Medic spanning from 1980 to
2018 available on Non-English journals and English/Non-English- MS worldwide accepted scientific
databases via electronic search (Elsevier, Google Scholar, PubMed, Scopus, Springer, Web of
Science, Wiley online library) and Ph.D. thesis databases (e.g., CKNI-China, JAIRO-Japan,
Shodhganga-India, Myto-Malaysia, etc.).
Results: Evidence suggests that the extracts and some compounds from. bursa-pastoris(L.) Medic
possessantimicrobial, anticancer, anti-inflammatory, smooth muscle contraction, infertility, antioxidant,
cardiovascular, sedative, hepatoprotective and acetylcholinesterase inhibitor properties. C.
bursa-pastoris, besides having pharmacological profile has an acceptable nutritional value also due
to its novel bioactive compounds such as phytosterols, phenolics, flavonoids, fatty acids, organic
acids, peptides and amino acids.
Conclusion: Scientific evidence suggests that there is a strong pharmacological potential in developing
C. bursa-pastoris (L.) According to the Medic, it is a drug which is used in the treatment of
various disorders from antimicrobial to anticancer therapy. C. bursa-pastoris can be a rich source
for the advancement of novel drugs to treat many human diseases due to the wide range of chemical
constituents present in the plant. Various ethnomedical uses and phytochemicals responsible for
these uses have not been evaluated yet to their fullest.