Background: Electrospun cellulose acetate (CA) nanofibrous membrane can be used in
many areas such as biomedicine, water treatment. However, due to the strong hydrogen-bond interaction,
the rare solvent can dissolve the CA and the resulting CA nanofibrous membranes always show
bad morphology and poor performance.
Aim: To research the effect of CaCl2-Formic acid (CaCl2-FA) solvent system on the morphology and
structure of CA nanofibrous membrane.
Method: CA nanofibrous membrane was fabricated with a two-step dissolution method using the first
step of CaCl2-FA solvent system followed by the second step of FA solvent solely. Subsequently, the
CA nanofibrous membrane morphology and structure property were systematically investigated.
Results: The results show that the CaCl2-FA can dissolve the CA efficiently. Additionally, the regenerated
CA nanofibers are well-formed under all the CA concentrations with controlling fiber diameter
ranging from 224.9 ± 38.6 nm to 367.8 ± 80.4 nm. The results suggest that this two-step dissolution
method can be an effective and alternative approach to dissolve CA and regenerate CA nanofibrous