Aims and objective: Benign Prostatic Hyperplasia (BPH) is a condition that causes
the proliferation of the cells of the prostate causing urine retention, renal insufficiency, bladder
calculi, recurrent Lower Urinary Tract Infections (LUTS) and in complicated cases, hematuria
with unbearable pain. The trial was conducted to study the safety and efficacy of novel herbal
product Verona anti- BPH capsules at a local clinic of Sharafi Goth, Karachi Pakistan.
Introduction: Benign Prostatic Hyperplasia (BPH) is one major condition. The prevalence of
the disease increases to around 8-60% in men at the age of 40 years which is caused mainly by
hormonal change, lifestyle changes or diet. The disease is mainly defined as increased cellular
proliferation of the prostate glands or an enlarged prostate. 50% men of age 65 years and
above of the total population of Pakistan are at risk of having Benign Prostatic Hyperplasia
Method: This was a single blind, placebo control phase I clinical trial. A total of 35 patients
were enrolled in the study, out of which 2 patients got dropped out. 23 patients received Verona
anti-BPH capsules and 10 patients received placebo. The sample paired t-test was applied
to evaluate the significant level.
Results: Verona Anti-BPH capsules were found safe and effective in the treatment of Benign
Prostatic Hyperplasia (anti-BPH).
Conclusion: Verona anti-BPH capsules were known to be effective with no harmful side effects.