Background: The resistance of Staphylococcus aureus to commonly used antibiotics is
linked to their ability to acquire and disseminate antimicrobial-resistant determinants in nature.
This study determined the antibiotic sensitivity profile of Staphylococcus aureus isolated from
milk samples of mastitic and healthy dairy cattle. Isolation and Identification of S. aureus was done
by Marphological and Biochemical characters.
Methods: The primary purpose of this study was to determine Antibiotic Sensitivity of Staphylococcus
aureus by using extracts of Prosopis juliflora, Cassia occidentalis and Tephrosia purpurea.
Antimicrobial properties of plant extracts were analyzed by determining Zone of Inhibition (ZOI)
and Minimum Inhibitory Concentration (MIC). Antibiogram pattern of the isolated Staphylococcus
aureus was observed to be Susceptible, Intermediate and Slight resistant by Prosopis juliflora,
Tephrosia purpurea and Cassia occidentalis respectively.
Results: From the results, it has been indicated that the extracts of Tephrosia purpurea, Prosopis juliflora
and Cassia occidentalis are having potential to use in the management of Staphylococcus aureus.
Conclusion: Further phytochemical analysis is required to identify the active components of plant
extracts showing antimicrobial activity.