In vitro Studies on Antimicrobial Sensitivity of Staphylococcus aureus from Prosopis juliflora, Cassia occidentalis and Tephrosia purpurea

Author(s): Aishwarya A. Andhare*, Ravindra S. Shinde

Journal Name: Anti-Infective Agents
Formerly Anti-Infective Agents in Medicinal Chemistry

Volume 18 , Issue 4 , 2020

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Graphical Abstract:


Background: The resistance of Staphylococcus aureus to commonly used antibiotics is linked to their ability to acquire and disseminate antimicrobial-resistant determinants in nature. This study determined the antibiotic sensitivity profile of Staphylococcus aureus isolated from milk samples of mastitic and healthy dairy cattle. Isolation and Identification of S. aureus was done by Marphological and Biochemical characters.

Methods: The primary purpose of this study was to determine Antibiotic Sensitivity of Staphylococcus aureus by using extracts of Prosopis juliflora, Cassia occidentalis and Tephrosia purpurea. Antimicrobial properties of plant extracts were analyzed by determining Zone of Inhibition (ZOI) and Minimum Inhibitory Concentration (MIC). Antibiogram pattern of the isolated Staphylococcus aureus was observed to be Susceptible, Intermediate and Slight resistant by Prosopis juliflora, Tephrosia purpurea and Cassia occidentalis respectively.

Results: From the results, it has been indicated that the extracts of Tephrosia purpurea, Prosopis juliflora and Cassia occidentalis are having potential to use in the management of Staphylococcus aureus.

Conclusion: Further phytochemical analysis is required to identify the active components of plant extracts showing antimicrobial activity.

Keywords: Zone of inhibition, antimicrobial-resistant, antimicrobial sensitivity, Staphylococcus aureus, antibiogram pattern, Prosopis juliflora, Cassia occidentalis, Tephrosia purpurea.

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Article Details

Year: 2020
Published on: 04 January, 2021
Page: [384 - 390]
Pages: 7
DOI: 10.2174/2211352518666200117095755
Price: $25

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