One of the organocatalysts 1,4-diazabicyclo[2.2.2]octane (DABCO) is an excellent solid
catalyst in a number of reactions. It is also a good nucleophile and a base in numerous reactions for the
synthesis of heterocycles. DABCO catalyzes many reactions like cycloaddition reactions, coupling reactions,
Baylis-Hillman reaction, Henry reaction, ring opening reactions, etc. One more advanced feature
of these reactions is that they proceed through environmental friendly pathway. DABCO has
more advantages than other organic catalysts because it is an inexpensive, non-‐toxic base, an ecofriendly
and a highly reactive catalyst for building of organic frameworks, which produce the desired
products in excellent yields with high selectivity. Many catalytic applications of DABCO have been
reported for the synthesis of an organic framework which has been discussed in this review.
Keywords: 1, 4-diazabicyclo[2.2.2]octane (DABCO), organic transformations, catalysis, environmentally friendly.
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