Repurposing Drugs for Skin Cancer

Author(s): Levon M. Khachigian*

Journal Name: Current Medicinal Chemistry

Volume 27 , Issue 42 , 2020

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Drug repurposing is the process of developing existing or abandoned drugs for a different disease. Repurposing can circumvent higher costs and times associated with conventional drug discovery strategies because toxicity and pharmacokinetics profiles are typically already established. This brief review focuses on efforts to repurpose drugs for skin cancer and includes reuse of antihypertensives, anthelmintics and antifungals among a range of other medicines. Repurposing not only ushers promising known drugs for new indications, the process of repurposing can uncover new mechanistic insights in the pathogenesis of disease and uncover new opportunities for pharmaceutical intervention.

Keywords: Drug repurposing, drug repositioning, melanoma, skin cancer, cancer, disease, melanoma.

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Article Details

Year: 2020
Published on: 16 December, 2020
Page: [7214 - 7221]
Pages: 8
DOI: 10.2174/0929867327666191220103901
Price: $65

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PDF: 27