Background: Takotsubo Cardiomyopathy (TTC) is an uncommon cause of acute reversible
ventricular systolic dysfunction in the absence of obstructive Coronary Artery Disease
(CAD). Typically manifesting as apical wall ballooning, TTC can rarely present atypically with
apical wall sparing.
Case Report: A 62-year-old female presented with complaints of chest pain and features mimicking
acute coronary syndrome. Coronary angiogram revealed no obstructive CAD and left ventriculogram
showed reduced ejection fraction, normal left ventricular apex and hypokinetic mid-ventricles
consistent with atypical TTC. The patient was discharged home on heart failure medications and a
follow-up transthoracic echocardiogram demonstrated improved left ventricular function with no
wall motion abnormality.
Conclusion: This case report provides an insight into the diagnosis and management of TTC in the
absence of pathognomic features.
Keywords: Tako tsubo, takotsubo cardiomyopathy, stress cardiomyopathy, atypical takotsubo, midventricular cardiomyopathy,
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