There are several protocols for the preparation of bicyclic derivatives; however, some methods
use dangerous and require special conditions. The aim of this study was to synthesize a new Dioxaspiro[
bicyclo[3.3.1]nonane-oxabicyclo[6.2.0]-deca-1(10), 8-dien-4-one (compound 8). Compound 8
was prepared using some reactions such as; i) etherification, ii) reduction, iii) amidation, iv) imination
and v) 2+2 addition. The chemical structure of 8 and its intermediaries were completely characterized
by spectroscopic techniques and elemental analysis. The synthesis showed a yield of 85% for compound
8. In this study, an easy method for the preparation of compound 8 is reported.