Marine Actinomycetes-derived Natural Products

Author(s): Chengfang Yang, Rui Qian, Yao Xu, Junxi Yi, Yiwen Gu, Xiaoyu Liu, Haobing Yu, Binghua Jiao, Xiaoling Lu*, Wei Zhang*

Journal Name: Current Topics in Medicinal Chemistry

Volume 19 , Issue 31 , 2019

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Graphical Abstract:


Abstract:

Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

Keywords: Marine actinomycetes, Secondary metabolites, Antibacterial activity, Antiviral activity, Cytotoxic activity, Lead compound.

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VOLUME: 19
ISSUE: 31
Year: 2019
Page: [2868 - 2918]
Pages: 51
DOI: 10.2174/1568026619666191114102359
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