Background: Breast plastic surgery is a rapidly evolving field of medicine. The modern view
of surgical trends reflects the desire to minimize complications and introduce advanced technologies.
These always will be priorities for surgeons. Reconstructive surgery, a branch of plastic surgery focusing
on restoration of lost functional and aesthetic component, seeks to enhance psychological rehabilitation
and improves the quality of life, as well as aesthetic recovery.
Objective: This review addresses the action of fibrin agents and their effect on the quality of surgical
Discussion and Conclusion: The fundamental goals for the surgeon are to perform a minimally traumatic
intervention and to prevent any form of complication. Achieving complete hemostasis is an intraoperative
necessity. Timely prevention of bleeding and hemorrhagic phenomena can affect not only
the outcome of the operation, but also the incidence of postoperative complications. Topics include the
integrity of microvascular anastomoses, tissue adhesion, and the incidence of seromas and hematomas
associated with fibrin glue usage. The literature on fibrin adhesives with respect to prevention of postoperative
complications, and the effectiveness with active drainage also are analyzed.