Background: The electrospinning and the bubble electrospinning provide facile ways for
the fabrication of functional nanofibers by incorporating rutin/hydroxypropyl-β-cyclodextrin inclusion
complex (RT/HP-β-CD-IC) in Polyvinyl Alcohol (PVA). Few patents on incorporation of rutin and cyclodextrin
in nanofibers has been reported.
Objective: The study aimed at increasing the loading amount of rutin in the electrospun nanofibers to
obtain ultraviolet resistant property.
Methods: Rutin was encapsulated in the cavity of RT/HP-β-CD and formed an inclusion complex.
Fourier Transform Infrared Spectroscopy (FTIR) and Differential Scanning Calorimeter (DSC) was
used to verify the formation of inclusion complexes.
Results: The results showed that the inclusion between rutin and HP-β-CD had been successfully
formed. The surface morphologies of nanofibrous membranes were characterized by Scanning Electron
Microscope (SEM), which indicated that adding RT/HP-β-CD inclusion complexes had little influence
on the morphologies and diameters of the fibers. Ultraviolet resistant results also confirmed the
inclusion complex had increased the loading amount in the final nanofibrous mats, and thus had good
ultraviolet resistant properties.
Conclusion: The formed inclusion complexes had obviously enhanced the loading amount of rutin in
electrospun PVA nanofibers, indicating that encapsulation of rutin in the cavity of HP-β-CD is a good
way to increase the loading amount.