Therapeutic Effects of Ziziphus jujuba Mill. Fruit in Traditional and Modern Medicine: A Review

Author(s): Zahra Sobhani, Sara Nikoofal-Sahlabadi, Mohammad S. Amiri, Mahin Ramezani, Seyed A. Emami*, Amirhossein Sahebkar*

Journal Name: Medicinal Chemistry

Volume 16 , Issue 8 , 2020

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Graphical Abstract:


Ziziphus jujuba Mill. belonging to the Rhamnaceae family, has been consumed since ancient times as a medicine and food. In the different traditional medical schools, Z. jujuba has been used to treat various diseases such as respiratory system diseases (asthma, cough, and laryngitis), gastrointestinal problems (constipation, colitis and liver diseases), as well as cardiovascular and genitourinary system diseases. From the perspective of Islamic traditional medicine (ITM), Z. jujuba fruit is an emollient, laxative, and maturative, it can purify blood and improve blood circulation, relieve internal heat and reduce inflammation. Some therapeutic uses of Z. jujuba such as antibacterial, antioxidant, sedative, hepato-protective, anti-hyperglycemic, and anti-hyperlipidemic activities have been shown in modern pharmacological studies. In the current study, traditional and ethno-medicinal uses, botany, phytochemistry and pharmacological activities of Z. jujuba were reviewed.

Keywords: Traditional medicine, Ziziphus jujuba, Rhamnaceae, jujube, food, flavonoids.

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Article Details

Year: 2020
Page: [1069 - 1088]
Pages: 20
DOI: 10.2174/1573406415666191031143553
Price: $65

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