Electrochemical-Based Biosensors: New Diagnosis Platforms for Cardiovascular Disease

Author(s): Fatemeh Yousefi, Ahmad Movahedpour, Zahra Shabaninejad, Younes Ghasemi, Shahram Rabbani, Ali Sobnani-Nasab, Soheila Mohammadi, Behzad Hajimoradi, Samaneh Rezaei, Amir Savardashtaki*, Majid Mazoochi*, Hamed Mirzaei*.

Journal Name: Current Medicinal Chemistry

Volume 27 , Issue 15 , 2020

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One of the major reasons for mortality throughout the world is cardiovascular diseases. Therefore, bio-markers of cardiovascular disease are of high importance to diagnose and manage procedure. Detecting biomarkers provided a promising procedure in developing bio-sensors. Fast, selective, portable, accurate, inexpensive, and sensitive biomarker sensing instruments will be necessary for detecting and predicting diseases. One of the cardiac biomarkers may be ordered as C-reactive proteins, lipoprotein-linked phospho-lipase, troponin I or T, myoglobin, interleukin-6, interleukin-1, tumor necrosis factor alpha, LDL and myeloperoxidase. The biomarkers are applied to anticipate cardio-vascular illnesses. Initial diagnoses of these diseases are possible by several techniques; however, they are laborious and need costly apparatus. Current researches designed various bio-sensors for resolving the respective issues. Electrochemical instruments and the proposed bio-sensors are preferred over other methods due to its inexpensiveness, mobility, reliability, repeatability. The present review comprehensively dealt with detecting biomarkers of cardiovascular disease through electro-chemical techniques.

Keywords: Cardiovascular disease, electrochemical biosensors, diagnosis, mortality, C reactive proteins, myeloperoxidase.

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Article Details

Year: 2020
Page: [2550 - 2575]
Pages: 26
DOI: 10.2174/0929867326666191024114207
Price: $65

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