A Novel Copper-Catalyzed Synthesis of N-Monosubstituted 2-Alkynimidamides from 1-Alkynes and Trichloroacetamidines

Author(s): Hossein Fasihi Dastjerdi, Manijeh Nematpour, Elham Rezaee, Mehdi Jahani, Sayyed Abbas Tabatabai*

Journal Name: Letters in Organic Chemistry

Volume 17 , Issue 9 , 2020

Become EABM
Become Reviewer

Graphical Abstract:


A one-pot Cu-catalyzed synthesis of functionalized alkynyl imidamide by terminal alkynes, trichloroacetonitrile and aniline or benzyl amine is reported. The compounds were produced via coupling reaction of terminal alkynes with trichloroacetamidine. This method was performed under mild, ligand-free conditions and easy work-up method.

Keywords: Terminal alkynes, copper iodide, alkynylimidamide, cross-coupling, aniline, one-pot reaction.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2020
Page: [704 - 708]
Pages: 5
DOI: 10.2174/1570178616666191023142821
Price: $65

Article Metrics

PDF: 15