eISBN: 978-981-14-2186-0, 2019 ISBN: 978-981-14-2185-3
This informative book provides a wealth of information on ovarian cancer. The book opens with a discussion of contemporary management of this disease with commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies. This is followed by presentations on ovarian cancer pathology. A chapter is devoted to methods of drug discovery through a functional genomics approach, with gene expression microarray databases available in public data repositories such as Public Gene Expression Omnibus (GEO} and validation using immunohistochemistry or Ingenuity Pathway Analysis (IPA). Next, the book explores the psycho-social issues that may be encountered by an ovarian cancer patient, including commentary on pain, fertility, anxiety, depression, demoralization, caregiver burnout, and end-of-life. The final chapter represents a step out from mainstream medical practice and provides an exposition of the mind-body interaction and the powerful role of belief in the healing process, with discussions of the placebo effect, nocebo effect, and numerous research studies that demonstrate the tremendous influence of our beliefs on our bodies and well-being.
Tamara L. Kalir Associate Professor of Pathology The Icahn School of Medicine at Mount Sinai USA.