Background: Breast cancer uncommonly occurs in young women, but, tends to be diagnosed
at a later stage and have a poorer prognosis than in older women. Standard screening
guidelines for this age group are not established and the radiologic features of breast cancer in
young women are not fully studied yet, because of the low incidence.
Objectives: To investigate the imaging findings for breast cancer in women aged 30 years or
younger and to correlate them with clinicopathologic features and immunohistochemical subtypes.
Methods: The study included 52 women with surgically confirmed breast cancer. The medical records
of the patients were retrospectively reviewed and the mammographic and ultrasonographic
findings were evaluated according to the fifth edition of the ACR BI-RADS lexicon.
Results: Most of the tumors in this study were presented as a self-detected mass (42/52, 80.8%)
and were of histologic grade III (31/43 invasive carcinoma, 72.1%) and the estrogen receptorpositive
subtype (32/52, 61.5%). The most common mammographic finding was an irregular
(19/24, 79.2%), indistinct (16/24, 66.7%), and hyperdense (20/24, 83.3%) mass. The ultrasonographic
findings were of an irregular (32/47, 68.1%), indistinct (19/47, 40.4%), and hypoechoic/
heterogeneous (40/47, 85.1%) mass with no posterior features (34/47, 72.3%). An
oval/round-shaped mass on ultrasonography was also correlated with triple-negative cancer
Conclusion: On mammography and ultrasonography, breast cancer in young women usually presents
as a mass with irregular shape and indistinct margin. Some radiologic findings could be used
to predict the molecular phenotype of the tumor.