Recent Developments in the Medicinal Chemistry for New Small-Molecule Therapeutics to Treat HIV-AIDS

Author(s): Mrinmoy Saha, Shreya Bhattacharya

Journal Name: Current Topics in Medicinal Chemistry

Volume 19 , Issue 18 , 2019

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Centre for Disease Control and Preventive (Available at:
HIV/AIDS: The Basics. (Available at:
(a)Pomerantz, R.J.; Horn, D.L. Twenty years of therapy for HIV-1 infection. Nat. Med., 2003, 9, 867-873.
(b)Lu, D.Y.; Wu, H.Y.; Yarla, N.S.; Xu, B.; Ding, J.; Lu, T.R. HAART in HIV/AIDS Treatments: Future trends. Infect. Disord. Drug Targets, 2018, 18(1), 15-22.
Zhan, P.; Pannecouque, C.; De-Clercq, E.; Liu, X. Anti-HIV drug discovery and development: Current innovations and future trends. J. Med. Chem., 2016, 59, 2849-2878.
Voshavar, C. Protease inhibitors for the treatment of HIV/AIDS: Recent advances and future challenges. Curr. Top. Med. Chem., 2019, 19(18), 1571-1598.
Suttisintong, K.; Kaewchangwat, N.; Thanayupong, E.; Nerungsi, C.; Srikun, O.; Pungpo, P. Recent progress in the development of HIV-1 entry inhibitors: From small molecules to potent anti-HIV agents. Curr. Top. Med. Chem., 2019, 19(18), 1599-1620.
Maeda, K.; Das, D.; Kobayakawa, T.; Tamamura, H.; Takeuchi, H. Discovery and development of anti-HIV therapeutic agents: Progress towards improved HIV medication. Curr. Top. Med. Chem., 2019, 19(18), 1621-1649.
Motati, D.R.; Uredi, D.; Watkins, E.B. The discovery and development of oxalamide and pyrrole small molecule inhibitors of gp120 and HIV entry – A review. Curr. Top. Med. Chem., 2019, 19(18), 1650-1675.

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Article Details

Year: 2019
Page: [1569 - 1570]
Pages: 2
DOI: 10.2174/156802661918191009110427

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