Current Disposal Practices of Unused and Expired Medicines Among General Public in Delhi and National Capital Region, India

Author(s): Sachin Manocha, Umesh D. Suranagi, Ravinder K. Sah*, Rakhamaji D. Chandane, Sumit Kulhare, Nitesh Goyal, Krishna Tanwar.

Journal Name: Current Drug Safety

Volume 15 , Issue 1 , 2020

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Graphical Abstract:


Abstract:

Background: Stocking unused or expired medicines or donating these to others can lead to accidental or inappropriate ingestion, increasing the risk of adverse drug reaction(s) and even lead to antibiotic resistance. Further improper disposal of expired or unused medicines is associated with environmental pollution, health hazards and damage to ecosystem. Ecopharmacovigilance is an important area in this context.

Objective: To explore the awareness and disposal practices of unused/expired in the general public.

Materials and Methods: The current study is an observational, cross-sectional, questionnaire-based study conducted in 956 medicine consumers in New Delhi and National Capital Region, India. The knowledge, attitude, and practice of consumers regarding the disposal of unused medicines were evaluated.

Results: The majority (89.9%) of consumers opined that expiry of medicine(s) meant for completion of shelf life, production of toxic chemical and loss of or decreasing of beneficial effects of medicines. Majority (87%) of the consumers stored medicines at home. Almost all (92.6%) of the consumers threw away the expired medicines after storing for few days. Consumers discarded the expired medicines mainly in household trash (73%). The majority (93%) of consumers were in favour of a government program to collect unused or expired medicines from their home.

Conclusion: The knowledge and practices of consumers towards disposal of unused and expired medicines needs to be improved. Health care professionals, government and policy makers should offer training to educate and guide the general public on safe and proper disposal practices of expired or unused medicines.

Keywords: Unused medicines, expired medicines, disposal practices, ecopharmacovigilance, general public, personal care products.

[1]
Daughton CG. Pharmaceutics and personal care product in the environment: Overarching issues and overview. 2001. Available from: http://www.oup usa.org/isbn/0841237395.html
[3]
Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med 2006; 19(6): 542-7.
[http://dx.doi.org/10.3122/jabfm.19.6.542] [PMID: 17090787]
[4]
Ruhoy IS, Daughton CG. Beyond the medicine cabinet: An analysis of where and why medications accumulate. Environ Int 2008; 34(8): 1157-69.
[http://dx.doi.org/10.1016/j.envint.2008.05.002] [PMID: 18571238]
[5]
Zuccato E, Castiglioni S, Fanelli R, Bagnati R, Reitano G, Calamari D. Risks related to the discharge of pharmaceuticals in the environment: Further research is needed. In: Kümmerer K, Ed. Pharmaceuticals in the Environment. Berlin, Heidelberg: Springer 2004; pp. 431-7.
[http://dx.doi.org/10.1007/978-3-662-09259-0_31]
[6]
Vollmer G. Disposal of pharmaceutical waste in households–a European survey. In: Kümmerer K, Hempel M, Eds. Green and Sustainable Pharmacy. Berlin, Heidelberg: Springer 2010; pp. 165-78.
[http://dx.doi.org/10.1007/978-3-642-05199-9_11]
[7]
Oaks JL, Gilbert M, Virani MZ, et al. Diclofenac residues as the cause of vulture population decline in Pakistan. Nature 2004; 427(6975): 630-3.
[http://dx.doi.org/10.1038/nature02317] [PMID: 14745453]
[8]
Jobling S, Williams R, Johnson A, et al. Predicted exposures to steroid estrogens in U.K. rivers correlate with widespread sexual disruption in wild fish populations. Environ Health Perspect 2006; 114(Suppl. 1): 32-9.
[http://dx.doi.org/10.1289/ehp.8050] [PMID: 16818244]
[9]
Ogunshe A, Adinmonyema P. Evaluation of bacteriostatic potency of expired oral paediatric antibiotics and implications on infant health. Pan Afr Med J 2014; 19(378): 378.
[http://dx.doi.org/10.11604/pamj.2014.19.378.2156] [PMID: 25977741]
[10]
Vuong T, Marriott JL. Unnecessary medicines stored in homes of patients at risk of medication misadventure. J Pharm Pract 2006; 36(1): 16-20.
[http://dx.doi.org/10.1002/j.2055-2335.2006.tb00879.x]
[11]
Aditya S. Safe medication disposal: Need to sensitize undergraduate students. Int J Pharm Life Sci 2013; 4: 2475-80.
[12]
Bhayana K, Rehan HS, Arora T. Comparison of the knowledge, attitude, and practices of doctors, nurses, and pharmacists regarding the use of expired and disposal of unused medicines in Delhi. Indian J Pharmacol 2016; 48(6): 725-8.
[http://dx.doi.org/10.4103/0253-7613.194846] [PMID: 28066115]
[13]
Abahussain EA, Ball DE. Disposal of unwanted medicines from households in Kuwait. Pharm World Sci 2007; 29(4): 368-73.
[http://dx.doi.org/10.1007/s11096-006-9082-y] [PMID: 17273906]
[14]
Bashaar M, Thawani V, Hassali MA, Saleem F. Disposal practices of unused and expired pharmaceuticals among general public in Kabul. BMC Public Health 2017; 17(1): 45.
[http://dx.doi.org/10.1186/s12889-016-3975-z] [PMID: 28061902]
[15]
Sonowal S, Desai C, Kapadia JD, Desai MK. Disposal of medicines by consumers at a tertiary care hospital regardingthe disposal of unused medicines. J Basic Clin Pharm 2017; 8(1): 4-7.
[http://dx.doi.org/10.4103/0976-0105.195079] [PMID: 28104967]
[16]
Vellinga A, Cormican S, Driscoll J, Furey M, O’Sullivan M, Cormican M. Public practice regarding disposal of unused medicines in Ireland. Sci Total Environ 2014; 478: 98-102.
[http://dx.doi.org/10.1016/j.scitotenv.2014.01.085] [PMID: 24530589]
[17]
Braund R, Peake BM, Shieffelbien L. Disposal practices for unused medications in New Zealand. Environ Int 2009; 35(6): 952-5.
[http://dx.doi.org/10.1016/j.envint.2009.04.003] [PMID: 19423167]
[18]
Auta A, Omale S, Shalkur D, Abiodun AH. Unused medicines in Nigerian households: Types and disposal practices. J Pharmacol Pharmacother 2011; 2(3): 195-6.
[http://dx.doi.org/10.4103/0976-500X.83290] [PMID: 21897719]
[19]
De Bolle L, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: A source of potential health threats? Ann Pharmacother 2008; 42(4): 572-9.
[http://dx.doi.org/10.1345/aph.1K533] [PMID: 18364405]
[20]
Lagishetty R, Nagarajan P, Vijayanandhan SS. Practice towards disposal of medicines (left out/expired drugs) among the patients visiting tertiary care teaching hospital and primary health centre in South India. Asian J Biochem Pharm Res 2013; 4: 175-82.
[21]
Ahmed R, Alareefi A. Patient’s opinion and practice toward unused medication disposal in Malaysia: A qualitative study. Thaiphesatchasan 2010; 34: 117-23.
[22]
Persson M, Sabelström E, Gunnarsson B. Handling of unused prescription drugs--knowledge, behaviour and attitude among Swedish people. Environ Int 2009; 35(5): 771-4.
[http://dx.doi.org/10.1016/j.envint.2008.10.002] [PMID: 19013646]
[23]
Prüss A, Giroult E, Rushbrook P. Safe management of wastes from healthcare activities. World Health Organization 1999.


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Article Details

VOLUME: 15
ISSUE: 1
Year: 2020
Page: [13 - 19]
Pages: 7
DOI: 10.2174/1574886314666191008095344

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