Introduction: Nowadays, the most common problem in teenage girls is them facing
menstrual disorders that develop secondary osteoporosis in their adolescent period. The locomotor
system disorder is noticed more often in girls with adolescence hormone pathology, than in the
population. This has an enormous human and socio-economic impact. Osteoporosis is estimated to
affect 200 million women worldwide.
Objective: The aim of this research is to determine the development of secondary osteoporosis in
girls during their adolescent period.
Materials and Methods: An analysis of 173 girls aged from 13 to 17 were under our supervision in
the children’s clinic sanatorium “Zdravnisa”. Girls were divided into four groups according to their
Results: As per the correlation analysis data, the influence of steroid hormones level on bone content
has a cumulative effect on girls.
Conclusions: For patients with oligomenorrhea, secondary amenorrhea, and polymenorrhea, there
were disordered correlations of gonadotropic hormones. Correlations between calcium, phosphorus,
and magnesium are disordered, which can be proof of mineralization processes disorder. As per the
correlation analysis data for the girls with adolescence pathology, there were revealed direct average
correlation connections between the concentration of steroid hormones and structural-functional
properties of bony tissue. Low concentration of progesterone in the blood of girls with adolescence
pathology is one of the main reasons for bone content deficit, development of osteoporosis, and