A convenient and efficient chiral CuFe2O4@SiO2-Mn(III) Ch.salen nanocatalyst has been
developed for the C-N cross-coupling reactions of aryl halides/ phenylboronic acid with N-heterocyclic
compounds in water and/or DMSO under mild conditions. The catalyst could be applied for the
N-arylation of a variety of nitrogen-containing heterocycles with aryl chlorides, bromides, iodides and
phenylboronic acid under mild conditions. Moderate to good yields were achieved for all substrates.
The structure of catalyst was characterized using various techniques including FT-IR, FE-SEM, EDX,
XRD, TEM and TGA. The catalyst can be simply recovered and reused for several times without significant
loss of activity.