Chitosan is a cationic polysaccharide and multi-potential polymer with the ability to interact with other
natural and synthetic polyanionic/polymeric compounds, with or without a cross-linking agent. It has been able to
composite nano-microparticles with a variety of features. This compound has the ability to carry quercetin, as an
anti-tumor subject, through the various epithelial systems and release in the sustained and controlled state to the
This paper reviews published studies on detailed physicochemical properties of chitosan and quercetin in the fight
against the tumor. This also focused on how the chitosan polymer interacts with other polymeric and polyanion
species in order to improve its efficiency to make a more suitable capsule or matrix for a variety of drugs, especially
quercetin, in oral delivery systems.