Aim: The objective behind this present work is the development and characterization of
silver nanoparticles from Dalbergia sissoo leaf extracts and the analysis of anticancer activity.
Methods: Silver nanoparticles were prepared by using the aqueous solution of Dalbergia sisoo
leaf extract and silver nitrate. The formation of nanoparticles was determined by the color change
during the preparation of plant extract to metal ion in a fixed ratio. The prepared nanoparticles
were then characterized by TEM, FTIR, DLS, XRD, and SEM. Silver nanoparticles were also
evaluated for anticancer activity.
Results: Synthesized silver nanoparticles were having good anticancer activity against MCF 7
cancer cell line as compared to the standard drug Doxorubicin.
Conclusion: The particle size of nanoparticles was found to lie in the range of 10 to 50 nm.